Best Fat Burner: A Pharmacist’s Opinion (2025)

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We studied 14 supplements sold online against 8 criteria and selected these 3 fat burners:

Best fat burner in capsule form 🥇
> Fat Burner – Nutri&Co

Best value for money
> Organic Green Tea – Dynveo

Best entry-level
> Active Burner – Nutrimea

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Best effective fat burner supplements

Our selection criteria

• Active ingredients: list of active ingredients contained in the supplement.
• Form and concentration of active ingredients: these two factors affect the product’s effectiveness.
• Farming method: organic, local, or intensive farming.
• Presence of additives: colorants, preservatives, sweeteners…
• Dosage: form of the dietary supplement (capsule, tablet, gummies…) and usage instructions.
• Price per day: the price for 1 day of treatment, with the daily dose recommended by the laboratory.
• Customer reviews: this average customer rating of the brand comes from the laboratory’s website, review platforms, or marketplaces like Amazon.
• Our opinion on the brand: based on the tests of dietary supplement brands we conduct each month and the analysis of 6 criteria such as transparency and expertise.

The selected supplements below are all made in France and are vegan.

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# Best fat burner in capsule form 🥇

The fat burner offered by Nutri&Co is particularly effective because it contains a patented active ingredient that has been the subject of numerous in vitro and in vivo scientific studies – unlike most supplements on the market.

Sinetrol® Xpur C is a patented complex of grapefruit and orange extracts, enriched with guarana, with a polyphenol content of 90%.

Its effectiveness has been proven in 5 clinical studies conducted on 300 people. Scientists observed an increase in resting metabolism of 180 kcal per day after 16 weeks and a targeted fat mass loss of 1.8 kg, leading to a slimmer figure.

The formula is supplemented by a green tea extract rich in EGCG, which works in synergy with Sinestrol®.

Nutri&Co is a reliable and transparent brand (read our full test here to learn more). Additionally, customer reviews are very positive.

This laboratory is based in Aix-en-Provence and places particular importance on the quality of active ingredients and the effectiveness of its dietary supplements.

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# Best value for money

Dynveo’s green tea extract offers an excellent concentration of 90% polyphenols and 10% in EGCG. 

The raw material is organic, the harvest is manual, and the active extraction is water-based, ensuring product quality preservation.

The Dynveo laboratory is located in the south of France. The products are guaranteed pure and free from controversial additives or GMOs. 

Dynveo is transparent about microbiological analyses and ensures the absence of pesticide residues or heavy metals in its products (check our full test here).

Use the promo code DARWIN101 to get a 10% discount (for orders over €75).

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# Best Entry Level

The Active Burner supplement by Nutrimea is a good alternative at a lower price.

It contains 5 ingredients with recognized fat-burning effects, including guarana, green coffee, and cola, which are rich in caffeine.

Thus, the caffeine content of the supplement is particularly high (151.11 mg / day), so it is not recommended for pregnant women and children under 12 years old.

Nutrimea is a quality French brand offering supplements concentrated in active ingredients at controlled prices. (our test here). Its product range is particularly broad.

Use the promo code DARWIN10 to get a 10% discount (no minimum purchase).

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How do fat-burning actives work?

They stimulate the metabolism

The basic metabolism corresponds to the amount of energy the body needs at rest. It gradually decreases over time, but also after a too restrictive diet: the body stores more and promotes weight gain.

Conversely, physical activity helps maintain our basal metabolism at a stable level. By stimulating and improving this metabolism, fat-burners increase the body’s pace.

The body burns more calories, even at rest. Fat is stored less in adipose tissues but used as energy.

They promote fat burning

Fat burners boost thermogenesis, the mechanism that induces heat production in the body. Thus, they increase body temperature and caloric expenditure.

At the same time, they influence the lipogenesis – lipolysis balance: lipogenesis ensures the dietary storage of lipids during digestion. If lipogenesis is greater than lipolysis, the balance is broken, causing fat storage.

Fat burners stimulate lipolysis, i.e., the activation of the fatty acid degradation process, lipids drawn from the triglyceride stock. These are an important energy reserve in adipose tissues.

They have an appetite suppressant effect

Some also have an appetite suppressant effect and contribute to a sensation of satiety. They allow better appetite control and limit snacking urges.

In this sense, they also contribute to weight loss.

They facilitate elimination

Several liters of water are filtered and reabsorbed by our blood vessels daily. Poor blood circulation and poor lymphatic drainage cause fluid retention in the tissues, thus increasing the cellulite phenomenon.

Through their draining and/or diuretic action, some actives capture excess toxins, fats, and fluids. They facilitate their elimination and help the body not to store them.

They can also have beneficial effects on intestinal transit. This improves the elimination of accumulated waste and contributes to a flat stomach.

How to fight against overweight?

Adopt a varied and minimally processed diet. 

Highlight seasonal fruits and vegetables, eat enough proteins (animal or plant-based), essential for maintaining muscle mass and reducing fat mass. Limit sweets, pastries. 

As for drinks, favor water, herbal teas, and tea. Coffee is not prohibited, as long as it is consumed reasonably and preferably in the morning or at noon.

Finally, do not opt for low-calorie diets! They stimulate the production of ghrelin, a hormone secreted in the stomach and responsible for food cravings.

Which nutrients should be prioritized?

Green Tea

It is the most common fat burner found in natural dietary supplements. Its leaves are rich in caffeine and catechins.

The major catechins present in green tea are EGCG: epigallocatechin gallate. These compounds are very powerful antioxidants.

As observed in this study, EGCG helps stabilize blood sugar levels and reduces food intake.

They increase thermogenesis and thus calorie expenditure, as shown in this clinical trial. This trial suggests that consuming green tea contributes to a reduction in body fat and may help reduce the risk of obesity and cardiovascular diseases.

Finally, green tea has diuretic properties. It promotes waste elimination and helps maintain a flat stomach. Matcha, a powder made from tea leaves highly concentrated in active ingredients, is a good option.

Guarana

Guarana is also very rich in caffeine, known here as “guaranine.” It is an excellent stimulant and energizer for metabolism.

It encourages the body to become active and burn more calories, even at rest. This effect is even more evident when combined with green tea: this placebo-controlled study showed that taking caffeine and EGCG capsules led to a significant increase in calorie expenditure over 24 hours.

Finally, as shown in this study, it regulates adipogenesis, meaning the storage of lipids.

Kola Nut

This nut is rich in caffeine and theobromine. These compounds give it stimulating and energizing properties. It facilitates fat metabolism and limits their storage.

Kola nut is often associated with green tea and guarana in fat-burning dietary supplements. It aids in slimming down and helps in weight control.

Konjac

This plant root contains fibers called glucomannans, which have the ability to swell in the stomach in the presence of water. This creates an almost immediate appetite suppressant effect.

As shown in a clinical study on 72 type II diabetics who received konjac for 65 days, it also promotes blood sugar regulation and has positive effects on cholesterol.

Carnitine

Carnitine is an amino acid involved in the fat-burning process.

It belongs to the amino acids known as “fat transporters.” It transports fatty acids to the mitochondria so that they are transformed into energy rather than stored. It is appreciated by athletes for weight loss and metabolism acceleration.

It is available as a supplement, but it is better absorbed through diet. Red meat is by far the main source, but it is also found in dairy products, avocados, and tempeh.

Minerals and Trace Elements 

A deficiency in certain minerals and trace elements seems to be linked to weight gain.

Magnesium, for example, is one of the essential minerals for the normal functioning of our body.

It participates in more than 300 enzymatic reactions in the body: it notably contributes to the body’s energy metabolism and muscle function, and various studies confirm its role in blood sugar regulation.

Thus, this review of trials indicates that magnesium supplementation in deficient or diabetic individuals could allow for a reduction in BMI (Body Mass Index) and waist circumference.

Zinc, for its part, is essential for processing fats and carbohydrates. It also supports amino acids in lipid metabolism.

A clinical trial was conducted on 40 people suffering from obesity. In addition to a low-calorie diet, subjects supplemented with 30 mg of zinc each day for 4 months observed a reduction in weight, BMI, and waist circumference, greater than those not supplemented. Their appetite measure was also lower.

Vitamins

Priority is given to vitamin C and vitamin B3 (or niacin).

Vitamin C promotes fat oxidation. It is also involved in the production of carnitine and norepinephrine. Located in adipose tissues, this compound triggers the lipolysis process and mobilizes fat reserves.

Vitamin B3 is involved in the breakdown of lipids. It transforms them into a source of energy for the body.

In what form?

In capsules and tablets

This is the most common format. Capsules and tablets have the advantage of being easy to take and tasteless. However, these supplements do not all have the same concentration of actives.

Make sure to choose a fat burner that is sufficiently potent and has good bioavailability. It should also be natural, without additives and preservatives. Preferably opt for plant-based and organic-certified capsules.

In powder

Guarana, amino acids, or even green tea are often offered in powder form. This format is minimally processed and generally well-concentrated in actives.

The powder mixes easily in a glass of water or fruit juice. It can also be added to smoothies, drinks, and protein shakes.

In gummies

Gummies are chewable candies. Those intended for fat burning contain various plant extracts, vitamins, and/or minerals that support metabolism and combustion.

These dietary supplements are fun, attractive, and tasty. However, they sometimes contain sugar. Therefore, they should be consumed in moderation, especially in a weight loss diet.

In ampoules

These are most often plant complexes. In ampoules, the fat-burning actives are present in aqueous extract form. This format is interesting for carrying out a treatment for a few days or weeks.

They generally contain green tea and guarana in concentrated form. Ampoules are easy to take: you just need to dilute them in a large glass of water.

Conservation is often limited, and the taste is more pronounced.

In liquid solution

The liquid form is reserved for aqueous plant extracts, caffeine, vitamin C, and amino acids like carnitine.

These drinkable solutions are often well-concentrated and directly absorbable by the body.

In tea and infusion

Fat-burning teas are composed of a mixture of plants such as green tea, guarana, or mate.

They can also contain diuretic plants and draining herbs like meadowsweet, hibiscus, mint, or verbena.

They generally need to be taken several times a day to hope for a significant effect, and the sometimes strong taste can deter some from using them.

Purchase criteria

1. Concentration in actives

Part of the effectiveness of the dietary supplement depends on its concentration in actives.

Favor products with the shortest possible list of ingredients to hope for a sufficient concentration in actives.

– 500 mg of green tea extract in capsules per day is recommended, or 2 grams (1 teaspoon) of tea leaves 3 times a day.

– 1000 mg of Konjac 3 times a day, with a large glass of water, to achieve the appetite suppressant effect.

– Zinc minerals should be taken at a content of 15 mg per day, and a supplementation of magnesium 300 mg per day is recommended as a 3-month treatment.

Finally, for other nutrients, like L-carnitine, there is no consensus regarding the recommended nutritional dosage. Feel free to seek advice from an informed healthcare professional.

2. Bioavailability

Maintain a maximum of 70° for the temperature of green tea infusions to preserve heat-sensitive active compounds. Above this temperature, there is a loss of vitamins and minerals present in the leaves.

Be cautious about the form of minerals:

– For magnesium: favor organic salts, which are better tolerated (magnesium citrate, malate) and chelated salts, such as magnesium bisglycinate.

– For zinc, prefer gluconate, picolinate, acetate, or zinc bisglycinate forms. 

In both cases, avoid oxide forms, which are insoluble in water and have laxative effects.

3. Cultivation Method

In general, prioritize loose plants from local and, if possible, organic agriculture, as they are less altered and have more effective active compounds.

4. Composition

Products combining a mix of plants and minerals are generally lower dosed than a dietary supplement with a single active ingredient. 

I recommend favoring products with a maximum of 5 active compounds: the concentrations will be sufficient to hope for a significant effect, and you will limit the intake of additives.

Dietary supplements indicated for weight loss generally contain a mix of active ingredients. Each of them has its own usage precautions and contraindications.

Some are contraindicated for pregnant and breastfeeding women. Medical advice is highly recommended for people suffering from chronic diseases and in case of associated medication treatment.

5. Price

Well-known laboratories offering quality products offer more expensive fat-burning supplements, and that’s normal. A higher price is generally justified by the quality (local, controlled, organic..) and the (high) titration of the ingredients used.

Be careful that a high price is not always synonymous with quality. Brands such as Brulafine or PhenQ, based abroad, offer products whose price is particularly high, for similar or even lower quality compared to significantly cheaper competing supplements.

Moreover, concerning Brulafine, customers often find themselves subscribed against their will to a weight-loss coaching application if they do not uncheck a box at the time of payment.

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Best fat burner in capsule 🥇

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Best fat burner in shot form

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Best value for money

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Best entry-level

Document prepared by Louise Talleu (pharmacist) and Julia Perez (health writer)

When you purchase the selected products, a commission may be provided to us to support the site, pay our writers, and ensure you receive quality information. This does not affect prices.