What is vitamin B12?
Vitamin B12, or “cobalamin,” is a water-soluble vitamin. Within the body, it plays a role in the process of cell division, the synthesis of proteins, and the construction of DNA.
It is also essential for the proper functioning of the nervous system and the formation of red blood cells.
It can be obtained through diet and the consumption of certain foods. Red meats and organ meats, seafood, fatty fish, eggs, and dairy products are good sources.
Taking a dietary supplement can also help meet daily requirements.
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Vitamin B12 deficiency is common, particularly among vegetarians, vegans, and plant-based eaters. Indeed, this vitamin is mainly found in animal-derived products.
The lack of cobalamin also affects people over the age of 65.
Insufficient intake can lead to inflammation and swelling in the joints. This then results in arthritic joint pain and cartilage wear.
What impact does it have on joint pain?
A deficiency can cause joint pain
Most severe joint pains are caused by an injury or chronic inflammation like arthritis.
But a vitamin B12 deficiency can also be a cause.
Indeed, it causes an increase in the level of homocysteine, a pro-inflammatory sulfur amino acid that accumulates in the blood. It is derived from methionine, which is synthesized by vitamin B12.
An excess of homocysteine (hyperhomocysteinemia) results in joint pain. It also reduces bone density and interferes with the production of collagen, essential to cartilage.
Finally, it increases the risk of osteoporosis as demonstrated by this study.
Sufficient consumption of vitamin B12 is therefore important to maintain balanced levels of homocysteine in the blood.
A deficiency accelerates cartilage wear
A lack of vitamin B12 can accelerate the wear and deterioration of cartilage. Indeed, it causes inflammation, swelling, and friction in the joints.
These repeated frictions are sources of pain, erodes and weakens the cartilage progressively. They increase the risk of rheumatoid arthritis.
As shown in this study, cobalamin is interesting for treating rheumatoid arthritis.