Eucalyptus: benefits, dosage, contraindications

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Eucalyptus is a genus of flowering trees and shrubs belonging to the Myrtaceae family. Eucalyptus is native to Australia but now grows in many tropical and subtropical climates. Eucalyptus leaves can be steam-distilled to extract eucalyptus oil. The parts of eucalyptus used in therapy are the leaf and the essential oil. Leaf constituents include the monocyclic sesquiterpenoid litseagermacrane, prenylated phloroglucinols, methylated flavones, and triterpenes. Other constituents include macrocoprenes. The oil contains terpenes such as 1,8-cineole (=Eucalyptol, at least 70%), pinenes, phellandrene, and limonene. Eucalyptus is used for many conditions: - Internal use Adjuvant treatment of chronic obstructive respiratory conditions, including bronchitis and asthma, as well as symptomatic relief of colds and catarrh of the upper respiratory tract. - External use Symptomatic treatment of colds and rheumatic disorders.

Other name(s) 

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Scientific name(s)

Eucalyptus globulus, Eucalyptus radiata

Family or group: 

Plants

Active ingredients:

Eucalyptol


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Asthma
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Preliminary clinical research suggests that eucalyptol, a constituent of eucalyptus oil, has mucolytic properties. When used orally, it may reduce the dosage of oral steroids in patients with severe asthma. ESCOP indicates eucalyptus oil for adjuvant treatment of chronic obstructive respiratory conditions, including bronchial asthma.

Posologie

posologieOral administration: leaf

posologie200 - 600 mg

formulationessential oil, dry extract


Bronchitis
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Some clinical research suggests that oral intake of a commercial product named GeloMyrtol®, containing essential oils from eucalyptus leaves, myrtle, sweet orange, and lemon peels, at 900-1200 mg/day for at least 2 weeks improves symptoms and reduces exacerbations of chronic and acute bronchitis. ESCOP indicates eucalyptus oil for the adjuvant treatment of chronic obstructive respiratory conditions, including bronchitis.

Posologie

posologieOral administration: leaf

posologie900 - 1200 mg

duration2 - weeks

formulationessential oil, GeloMyrtol®


Synergies


Gingivitis
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Preliminary clinical research shows that chewing gum containing 0.4 to 0.6% eucalyptus extract five times a day for four days improves gingivitis.

Posologie

posologieBuccal administration: leaf

formulationessential oil


Dental plaque
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Preliminary clinical research shows that chewing gum containing 0.3 to 0.6% eucalyptus extract 3 to 5 times a day for 4 to 12 weeks reduces dental plaque compared to placebo.

Posologie

posologieBuccal administration: leaf

formulationessential oil


Cold
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EMA indicates that eucalyptus oil is a traditional medication used to relieve cough associated with colds. ESCOP recommends it for symptomatic relief of colds and catarrh of the upper respiratory tract.

Posologie

posologieOral administration: leaf

posologie200 - 1000 mg

formulationessential oil, dry extract


Properties


Mucolytic

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Thanks to its high content of 1,8-cineole (eucalyptol), the essential oil is expectorant and mucolytic, it thins bronchial secretions to facilitate their expulsion. It also promotes the relaxation of smooth muscles of the airways.

Usages associés

Asthma, Bronchitis, Cold

Anti-inflammatory

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Eucalyptus essential oil (EO) contains 60 to 90% eucalyptol (1,8-cineole), and it has been shown that eucalyptol has analgesic and anti-inflammatory effects. Preliminary research suggests that eucalyptol may block the production of arachidonic acid metabolites involved in pain. It may also inhibit cyclooxygenase pathways. Eucalyptol and other constituents also seem to inhibit the production of cytokines responsible for inflammation, such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, leukotriene B4, and thromboxane B2. Besides the EO, ethanolic extracts of eucalyptus leaves also appear to have anti-inflammatory activity. This could explain its use in asthma.

Usages associés

Asthma, Bronchitis, Cold

Antiparasitic

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Eucalyptus oil is used in some topical solutions against head lice. The ovicidal effects of terpenes present in the oil have been demonstrated in vitro.

Usages associés

Lice

Antimicrobial

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Eucalyptus leaf extracts and their isolated components appear to have antimicrobial and antifungal activity.

Usages associés

Gingivitis, Dental plaque

Analgesic

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The essential oil is traditionally recommended for the symptomatic relief of localized muscle pain.

Usages associés

Rheumatism

Hypoglycemic

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An aqueous extract of eucalyptus leaves appears to have hypoglycemic activity. Preliminary research shows that it increases insulin secretion and improves glucose absorption and metabolism by muscles.


Safety dosage

Adults from 12 years: 200 mg - 1000 mg

For oral use, single dose: 100-200 mg, 2 to 5 times a day For topical use, a few drops on the chest or back, 2 to 3 times a day. Single dose for semi-solid dosage forms (10% eucalyptus oil): apply a thin layer on the chest and back, 2 to 3 times a day.

Children from 4 to 12 years:

Topical use only.


Interactions

Médicaments

Aminopyrine: moderate interaction

In human studies, inhalation of 1,8 cineole increased the disappearance of plasma aminopyrine.

Amphetamines: weak interaction

Animal research suggests that eucalyptol inhalation may reduce blood levels of amphetamines.

Antidiabetic: weak interaction

Animal research suggests that eucalyptus leaf may have hypoglycemic activity and could have additive effects when used with antidiabetic medications.

Pentobarbital: moderate interaction

Animal research suggests eucalyptol inhalation reduces the level of pentobarbital reaching the brain.


Precautions

Type 2 diabetes: use with caution

Preliminary research suggests that eucalyptus leaves may have hypoglycemic activity and could theoretically have cumulative effects when used with antidiabetic medications. Seek medical advice before any use.

Allergies: avoid

Eucalyptus and tea tree oils share many constituents. If a patient is allergic to eucalyptus oil, cross-reactivity with other essential oils, including tea tree oil, is possible. Certain compounds such as 1-8-cineole (eucalyptol), limonene, and beta-caryophyllene are present in almost all essential oils and may account for the observation that many patients exhibit cross-reactivity to more than one essential oil.

Children aged 2 to 4 years: avoid

Use in children between 2.5 and 4 years has not been established due to lack of data.

Breastfeeding women: avoid

Not enough data, avoid as a precaution.


Contraindications

Infants up to 30 months: prohibited

Contraindicated for children under 30 months because there's a risk that preparations containing 1,8-cineole, like other essential oils, might induce a laryngospasm.

Pregnant women: prohibited

Eucalyptus oil is not indicated for pregnant women.