L-Cysteine: Benefits, Dosage, Contraindications
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Amino Acids
Indications
Rating methodology
EFSA approval.
Hair Beauty, Skin Healing ✪✪✪✪✪
L-Cysteine is consumed for its benefits on skin and hair beauty. In cosmetics, L-Cysteine is incorporated into supplements for its ability to promote scalp health and hair strength, as it is essential for keratin synthesis, a protein that strengthens hair. L-Cysteine helps reduce hair loss and improve hair texture. For the skin, it supports collagen production, enhancing skin elasticity and texture. Its antioxidant properties combat free radical damage, promoting healthy skin.
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Smoking Cessation ✪✪✪✪✪
Preliminary clinical studies have shown that using a slow-release tablet containing 3 mg of L-Cysteine with each cigarette for 6 months does not increase smoking cessation chances compared to a placebo. A more qualitative study conducted by the same research group showed that using this tablet increases smoking cessation chances by about 51% compared to a placebo.
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Slow-release L-Cysteine (Acetium®) Lozenge Is an Effective New Method in Smoking Cessation. A Randomized, Double-blind, Placebo-controlled Intervention
Elimination of Cigarette Smoke-derived Acetaldehyde in Saliva by Slow-release L-Cysteine Lozenge Is a Potential New Method to Assist Smoking Cessation. A Randomised, Double-blind, Placebo-controlled Intervention
Skin Health ✪✪✪✪✪
A randomized controlled study evaluated the effect of L-Glutathione and L-Cysteine supplementation on skin lightening in 124 women aged 30 to 50 with at least one dark spot on the face. The results showed that the combination of L-Cysteine and L-Glutathione lightened the skin on the cheeks and lower forearm. No effect was observed with the placebo.
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Alcoholism ✪✪✪✪✪
A small clinical study showed that an immediate-release product containing L-Cysteine (1200 mg) in combination with other ingredients reduced hangover symptoms like nausea, headaches, stress, and anxiety modestly when taken six times between 7 PM and midnight in conjunction with alcohol (1.5 g/kg over 3 hours), compared to a placebo. However, other researchers have questioned the validity of the statistical methods used in this study and suggest that not all noted results were statistically significant.
Posologie
Properties
Antioxidant
L-Cysteine, a precursor of glutathione, methionine, and taurine, plays a key role for its antioxidant effects. In humans, L-Cysteine intake improved antioxidant status after athletic performance. In animal studies, L-Cysteine modestly reduced levels of certain free radicals and oxidative markers in brain tissue and increased antioxidant activity. It also slightly increased the activities of the antioxidant enzymes catalase and glutathione reductase, although it had no effect on other oxidation markers.
Neurological
Acting as a neuromodulator, L-Cysteine is essential for glutathione synthesis, playing a role in redox balance. In laboratory studies, it antagonizes GABA-alpha receptors. Additionally, L-Cysteine has been studied for alcohol use disorder. A reduction in the motivation to self-administer ethanol was found in animal models. However, neurotoxic effects have been observed, possibly due to the formation of L-Cysteine metabolites.
Usages associés
Safety dosage
Adult: 500 mg - 1200 mg
There is no typical dosage. Dosages used in studies range from 500 mg to 1200 mg.