Lavender: Benefits, Dosage, Contraindications

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Lavender is a perennial aromatic plant native to Mediterranean regions such as France and Spain. Its name derives from the Latin "lavare", meaning "to wash", referring to its historical use as a bath additive for its antiseptic qualities in ancient Greek and Roman civilizations. Since antiquity, lavender has also been used for its medicinal virtues, including the treatment of pain, cramps, and seizures. Nowadays, lavender is widely appreciated in aromatherapy for its benefits. It is primarily exploited in two forms: dried flowers and essential oil. Lavender flowers contain between 1 and 3% essential oil, with main components such as linalool and linalyl acetate, along with cineole and camphor. These substances confer significant antibacterial properties to lavender. In therapeutics, lavender is used for its relaxing and sedative effects. It helps to soothe agitation, insomnia, and functional abdominal disorders. Lavender-based preparations can be administered in the form of tea, used in inhalations, or applied locally. Recent studies support its use in treating anxiety and reducing the severity of migraines and menstrual pain, especially when applied in abdominal massage.

Other name(s) 

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Scientific name(s)

lavandulae flos, Lavandula angustifolia

Family or group: 

Plants

Active ingredients:

Camphor

Linalool

Rosmarinic Acid

Linalyl acetate


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Emotional balance
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Lavender is recognized for its calming properties, used in aromatherapy to reduce stress and anxiety. According to ESCOP, it's recommended for treating mood disorders such as agitation and insomnia. Studies show that lavender essential oil, notably the Silexanae formulation, can significantly improve symptoms of anxiety and depression when used in inhalation or orally. These beneficial effects on emotional well-being support its traditional and scientifically approved use in managing stress and promoting mental health.

Posologie

posologieBy Inhalation, oral, cutaneous

posologie80 mg

formulationLaseaxanae, infusion, essential oil, dry extract


Anxiety
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Studies on the anxiolytic effects of lavender, particularly Silexan® lavender oil, show promising results for anxiety management. Research, primarily conducted using Silexan® capsules dosed at 80-160 mg per day over 6 to 10 weeks, indicates a significant improvement in anxiety compared to placebo. However, the small sample sizes and study heterogeneity limit the generalization of these results. Studies comparing Silexan® to conventional medications such as lorazepam and paroxetine reveal comparable effectiveness in reducing anxiety symptoms.a0 Moreover, aromatherapy through inhalation or massage with lavender essential oil also appears to moderately reduce anxiety in chronic or situational contexts, often in comparison with an inactive control. While there is limited evidence for other forms of oral lavender administration, one study suggests that a dried lavender flower extract at 500 mg twice daily may reduce anxiety. The varying quality of research in this area highlights the need for more rigorous methodologies to confirm these effects. The combination of lavender oil with other essential oils such as bergamot is also explored, suggesting potential synergistic effects for improving anxiety and other mental health parameters. Lavender essential oil has been compared with other oils like Damask rose oil. A small double-blind randomized study concludes that Damask rose aromatherapy was more effective than lavender in reducing anxiety.

Posologie

posologieBy Inhalation, oral, topical route

posologie80 mg

formulationLaseaxan®, essential oil, dry extract


Synergies


Depression
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Research on the effects of lavender against depression shows mixed, but overall promising results, particularly with lavender essential oil in the form of Silexan® capsules. A meta-analysis on patients with mild to severe depression indicates that orally taken lavender, whether in oil or powder form, is moderately more effective than a control group in reducing depression symptoms. The studied doses vary, including lavender powder at 1-2 g per day for 8 weeks and lavender oil at 80 mg per day over 70 days. Lavender oil aromatherapy has also been evaluated in several studies, with a meta-analysis showing moderate efficacy in comparison to various controls, though the studies are not specifically focused on depressed patients. Moreover, studies on combinations of lavender with other essential oils (bergamot, orange) or plant extracts (Chinese dodder) show improvements in depressive symptoms, suggesting possible synergistic effects. For example, taking 5 ml of a syrup containing lavender flower extract and dodder extract twice daily for 6 weeks seems to reduce depression similarly to citalopram 20 mg per day, according to a small clinical study.

Posologie

posologieBy Inhalation, oral, topical route

posologie80 mg

formulationLaseaxan®, essential oil, dry extract


Synergies


Dysmenorrhea
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Clinical research indicates that lavender oil aromatherapy may alleviate symptoms of dysmenorrhea. One study shows that inhaling three drops of lavender oil applied on cotton for 30 minutes at the start of menstruation modestly reduces pain compared to the scent of diluted milk. Another similar study reports a reduction in abdominal and back pain through lavender oil inhalation. Additionally, abdominal massage with lavender essential oil has shown a moderate reduction in pain immediately after the treatment. In combination, a study used topical aromatherapy in the form of abdominal massage with lavender oil, clary sage, and rose, showing a significant decrease in the severity of menstrual cramps.

Posologie

posologieBy Inhalation, topical route

posologie3 drops

formulationessential oil


Synergies


Hair Loss
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A randomized clinical study examined the effectiveness of scalp massage with essential oils of thyme, rosemary, lavender, and cedar in 86 patients with alopecia, revealing a significant improvement in hair growth after 7 months.

Posologie

posologieBy topical route

formulationessential oil


Synergies


Sleep Disorders
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Sleep disorders and insomnia can be moderately improved by lavender oil aromatherapy, although study results are mixed and improvements often minimal. Several clinical studies suggest that lavender oil might improve sleep quality in some individuals. For example, a study on healthy students demonstrated that a patch infused with lavender oil, used in addition to good sleep hygiene practices, improved self-reported sleep quality. Moreover, in nursing homes, placing a few drops of lavender oil on a pillow near the bed improved sleep quality and reduced fatigue compared to a control group. However, lavender aromatherapy generally does not improve the sleep of hospitalized patients, despite some modest beneficial effects observed in certain conditions. According to ESCOP, lavender oil and flower infusions are recommended to treat symptoms of mood disorders such as restlessness or insomnia.

Posologie

posologieBy Inhalation, oral, topical route

posologie80 mg

formulationinfusion, essential oil, dry extract


Migraine
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A small clinical study showed that rubbing 2-3 drops of lavender oil for inhalation for 15 minutes significantly reduced the severity of migraine compared to controls. The study showed that out of 129 headache episodes, 92 fully or partially responded to lavender, compared to 32 out of 64 headaches for the placebo group. In other words, the percentage of subjects who responded positively to the treatment was significantly higher in the lavender group than in the placebo group.

Posologie

posologieBy inhalation

formulationessential oil


Joint pain, Muscle pain
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Lavender essential oil may provide relief from muscle and joint pain. A controlled study showed that eight acupressure sessions with lavender oil over three weeks effectively reduced pain, neck stiffness, and stress in adults suffering from subacute nonspecific neck pain. Furthermore, a small clinical study on patients with osteoarthritis revealed that self-massage with 5 mL of 3% lavender oil applied to the knee three times a week for three weeks decreased pain by 23% compared to massage with a placebo oil, and by 36% compared to no treatment. However, the beneficial effects seem to decrease after the end of the treatment.

Posologie

posologieTopical

formulationessential oil


Lice
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Clinical studies have shown that using lavender oil combined with tea tree oil can reduce the number of live head lice (but not nits) compared to control. The application of this combination three times a week also appears to improve lice eradication compared to bi-weekly treatments based on pyrethrin and piperonyl butoxide.

Posologie

posologieTopical

formulationessential oil


Synergies


Restless Leg Syndrome
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Restless Leg Syndrome is a neurological condition characterized by an irresistible urge to move the legs, often accompanied by unpleasant sensations. Symptoms typically intensify during periods of rest or at night. Preliminary studies suggest that massage aromatherapy with lavender oil could be beneficial for patients with restless leg syndrome, particularly those undergoing dialysis. Several small clinical studies have shown that foot or lower leg massage with lavender oil during hemodialysis sessions reduces the severity of restless leg syndrome by up to 45% compared to usual care, massage without oil, or a baby oil-based placebo. Dosages generally varied between 10 and 15 mL of 1.5% or 5% lavender oil for 10 to 45 minutes during three to four weeks of treatment. However, massage with lavender oil did not show significant advantage over 2% glycerine oil or 1.5% sweet orange oil for reducing the severity of restless leg syndrome.

Posologie

posologieTopical

posologie10 - 15 mL

formulationessential oil


Insect bites
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Lavender essential oil is used to treat insect bites due to its analgesic, anti-inflammatory, and antihistamine properties. It reduces swelling and skin irritation, offering quick relief. A few drops applied directly or diluted in a carrier oil effectively relieve itching and inflammation.

Posologie

posologieTopical

formulationessential oil


Properties


Sedative

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The sedative properties of lavender, particularly its essential oil rich in linalool and linalyl acetate, are well-documented in numerous studies. These components act in a dose-dependent manner, reducing caffeine-induced hyperactivity in mice and modulating various stress-related hormonal responses. Inhaling lavender oil has also shown a dose-dependent anticonvulsant effect in rats and mice. In humans, inhaling lavender promotes relaxation and sedation, modifies EEG responses (electroencephalogram, recording brain's electrical activity), improves sleep quality and increases alertness upon waking. Studies show that intermittent exposure to lavender can increase the proportion of deep sleep and reduce cortisol levels, contributing to a calmer and more vigorous state of mind in healthy volunteers.

Usages associés

Sleep disorders, Emotional balance

Anxiolytic

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The anxiolytic effect of lavender is supported by experimental studies. For example, lavender oil and its main constituents significantly reduced anxiety in rats, with results comparable, though less pronounced, to those of benzodiazepines. These effects have been attributed to linalool and linalyl acetate. Lavender's mechanism of action involves the inhibition of the hypothalamus-pituitary-adrenal axis and reduction of cortisol release, while increasing serotonin secretion by the adrenal gland, contributing to anxiety relief. Lavender's components, such as linalool and linalyl acetate, also act as sedative and anxiolytic agents by influencing gamma-aminobutyric acid (GABA) in the central nervous system. Research on humans inhaling lavender has shown that it can reduce heart rate and blood pressure, as well as improve mood. Lavender may enhance parasympathetic nervous system activity, potentially reducing stress response in the body.a0

Usages associés

Anxiety, Depression, Emotional balance

Dermatological effect

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Lavender has beneficial effects on hair growth and wound healing. Preliminary animal and clinical research has revealed that topically applied lavender oil may accelerate healing of recurrent aphthous ulcers. This effect may be due to the antibacterial and anti-inflammatory properties of lavender oil.

Usages associés

Hair loss

Antimicrobial

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Lavender oil, known for its antibacterial activity, has demonstrated effectiveness in the laboratory against various pathogens, including antibiotic-resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus. It also possesses antifungal properties, targeting fungi like Candida albicans by inhibiting germ formation and hyphal elongation at low concentrations, which can be useful for limiting fungal progression. Additionally, lavender oil, often used in synergy with tea tree oil, has proven effective against fungi responsible for ringworm and onychomycosis.


Analgesic

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Lavender essential oil is known for its analgesic properties, which help relieve pain. Studies have shown that inhaling lavender can reduce postoperative pain and headaches, while topical application can relieve muscular and joint pain.

Usages associés

Dysmenorrhea, Migraine

Musculoskeletal effects

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Research has shown that lavender can have spasmolytic effects on smooth muscles, meaning it can help reduce muscle spasms. Laboratory studies have revealed that lavender's component, cineole, can inhibit acetylcholine-induced muscle contractions. Lavender might be useful in treating muscular pain and cramps, as well as digestive disorders such as intestinal spasms.

Usages associés

Dysmenorrhea, Joint pain


Safety dosage

Adult from 12 years:

- Infusion (tea): 1.5 g of dried flowers in 150 ml of water, or 1 to 2 teaspoons of lavender flowers or leaves in a cup of boiling water, infused for 5 to 10 minutes and filtered before drinking. - Internally E.O.s: 1-4 drops (20-80 mg) on a sugar lump or neutral tablet. - External use: mix 20 drops of oil with 20 ml of a carrier oil such as almond oil. Can be applied neat to insect bites. - For the bath: 20 to 100 g of lavender flowers are generally infused in 2 L of boiling water, filtered, and then added to bath water. You can also add 5 to 7 drops to the bath and stir to mix the oil with the water. - Diffusion: use 2 to 4 drops of lavender oil in an appropriate oil diffuser or on a pillowcase to promote sleep. Lavender oil is quickly absorbed through the skin, and the components linalool and linalyl acetate have been detected in the blood 5 minutes after administration.

Child from 6 to 12 years:

Clinical studies have used lavender oil in aromatherapy with apparent safety for single doses lasting up to 2 minutes.


Interactions

Médicaments

Central nervous system depressants: weak interaction

Laboratory studies suggest lavender has sedative effects, but clinical studies on patients taking oral lavender oil at a dose of 160 mg for 10 weeks or lavender flower powder at a dose of 1 gram per day for 2 months have not reported side effects such as drowsiness, sedation, or sleepiness. However, there are still concerns that higher doses or different lavender preparations could have additive effects with central nervous system depressant drugs.


Precautions

Pregnant women: Use with caution

Initial clinical studies suggest the use of lavender essential oil during labor by inhalation does not present apparent adverse effects for newborns. However, it is important to be cautious regarding the use of essential oils during pregnancy. Therefore, it is recommended to consult a physician before use.

Breastfeeding women: Use with caution

There is not enough available data. Use with caution.