Plantain: benefits, dosage, contraindications

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Plantain is a perennial herbaceous plant, widespread throughout temperate Europe and Asia, growing in both wild and cultivated lands. It has short roots bearing rosette-shaped leaves; these broad, undivided leaves are used to soothe insect and nettle stings. Historically recognized for its medicinal properties, plantain has been used since antiquity for its antihistaminic and anti-infectious effects, now confirmed by scientific studies. Plantain is rich in various bioactive components, including iridoids like aucuboside, flavonoids, phenolic acids, and mucilages that contribute to its therapeutic effects. The leaves, mainly used in phytotherapy, should contain at least 0.5% aucuboside to ensure their effectiveness. In phytotherapy, plantain is used in several forms: infusions, decoctions, in salads or fresh juice to address various ailments, such as mucosal inflammations or skin disorders. Plantain is often included in the composition of cough syrups sold in pharmacies.

Other name(s) 

Broadleaf plantain

Scientific name(s)

Plantago lanceolata, Plantago major

Family or group: 

Plants

Active ingredients:

Iridoids

Phenolic acids

Mucilages

Tannins

Aucuboside


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Cough
✪✪✪✪

Plantain is traditionally used to relieve dry cough due to its emollient properties. The mucilages in the leaves help soothe irritated mucous membranes of the respiratory tract, thus reducing the frequency and intensity of coughing.

Posologie

posologieOral route: leaf

posologie2 - 4 g

formulationinfusion


Pharyngitis, Bronchitis
✪✪✪✪

For pharyngeal inflammation and mild bronchitis, plantain offers a soothing effect. Its components, notably iridoids like acteoside, reduce inflammation.

Posologie

posologieOral route: leaf

posologie2 - 4 g

formulationinfusion


Gastritis
✪✪✪✪

Plantain possesses anti-inflammatory and emollient properties that can help alleviate gastritis symptoms.

Posologie

posologieOral route: leaf

posologie2 - 4 g

formulationinfusion


Insect stings
✪✪✪✪

Thanks to its anti-inflammatory and antihistamine properties, plantain is effective against itching and irritation caused by insect stings. The local application of leaves or extracts can provide quick relief.

Posologie

posologieCutaneous route: leaf

posologie2 - 4 g

formulationpoultice, fluid extract


Acne
✪✪✪✪

The antibacterial properties of plantain help combat acne by reducing infection and inflammation. Topical application can help purify the skin and prevent breakouts.

Posologie

posologieCutaneous route: leaf

posologie2 - 4 g

formulationpoultice, fluid extract


Stomatitis
✪✪✪✪

Plantain offers benefits due to its healing and anti-inflammatory effects. Gargles or direct applications of plantain extracts can reduce pain and accelerate the healing of lesions.

Posologie

posologieOral route: leaf

posologie2 - 4 g

formulationpoultice, fluid extract


Properties


Antihistamine

full-leaffull-leafempty-leafempty-leaf

Plantain shows strong antihistamine activity, mainly thanks to its extracts inhibiting up to 80% of histamine release related to IgE antibodies, effectively contributing to reducing allergic reactions. This notable inhibition, observed even at low concentrations, supports its traditional use against allergies. Furthermore, plantain extracts also modulate inflammation by inhibiting key enzymes such as NO synthase and cyclooxygenases (COX-1 and COX-2) in macrophages. These properties, combined with bronchodilator effects, reinforce its role in treating allergic respiratory disorders.

Usages associés

Cough, Insect stings

Antibacterial

full-leaffull-leafempty-leafempty-leaf

Plantain demonstrates strong antibacterial activity, thanks to its compounds such as aucuboside which transforms into bactericidal dialdehyde. It is effective against a variety of pathogenic bacteria, including Staphylococcus aureus and Escherichia coli, making the plant useful in treating skin and other bacterial infections.

Usages associés

Acne

Anti-inflammatory

full-leaffull-leafempty-leafempty-leaf

Plantain shows significant anti-allergic and analgesic effects, reducing cough by 66%. It contains compounds such as acteoside and ursolic acid which inhibit the COX-2 enzyme, thus reducing the production of inflammatory molecules. A plantain extract reduced pro-inflammatory cytokines and improved the regulation of anti-inflammatory hormones in animal models.

Usages associés

Cough, Pharyngitis, Stomatitis

Digestive effect

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Plantain is beneficial for the digestive system due to its emollient and antispasmodic effects. The mucilages contained in the plant soothe irritated mucous membranes of the gastrointestinal tract, reducing inflammation and calming spasms, which helps relieve digestive disorders like gastritis.

Usages associés

Gastritis

Healing

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Plantain plays a notable role in healing, traditionally used for its beneficial effects on wounds. Its anti-inflammatory properties help reduce symptoms such as redness, fever, swelling, and pain. An animal study demonstrated that the aqueous extract of plantain could effectively replace silver sulfadiazine, particularly at a concentration of 50%, in the treatment of burns. Polyphenols, especially plantamajoside, are recognized for their healing virtues, facilitating the repair and regeneration of damaged tissue.

Usages associés

Acne

Gastroprotective

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Traditionally used to treat gastric ulcers, plantain shows significant efficacy in preventing and reducing ulcers. This activity is mainly attributed to the inhibition of acid secretion and the protective effect of its compounds on the gastric mucosa, thus reducing inflammation and promoting the healing of ulcerated tissues.

Usages associés

Gastritis


Safety dosage

Adult:

- Dry powder: 3 g - Leaf infusion: 2 to 4 g of leaves for 150 mL of boiling water, then filtered after 10 minutes. - Mother tincture: 3 times 75 to 100 drops per day. - Fresh juice: 1 to 2 teaspoons 2 to 3 times a day.


Contraindications

Pregnant woman: prohibited

Some data suggest that plantain affects the uterine muscle tone.