Meadowsweet: Benefits, Dosage, Contraindications

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Meadowsweet is a perennial herbaceous plant (and honey-producing) common in wet environments across Europe, Asia, and even America. The Latin name "Spiraea" comes from the spiral shape of its fruits. The discovery of salicylic acid from meadowsweet gave its name to aspirin (a for "acetyl" and spir for "spiraea"). The flowering tops are the parts used in therapy and are harvested in June/July at the start of flowering. Meadowsweet contains ascorbic acid, coumarin, flavonoids (spiraeoside, rutin, hyperoside, and avicularin), heparin, mucilages, phenolic acids, phenolic glycosides (including spiraeine, monotropine, and gaultherine), phenol acids: vanillic acid, derivatives of salicylic acid. Its essential oil contains salicylic aldehyde, methyl salicylate... Meadowsweet is known for its diuretic, analgesic, and anti-inflammatory properties.

Other name(s) 

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Scientific name(s)

Spiraea ulmaria; Filipendula ulmaria

Family or group: 

Plants

Active ingredients:

Salicin


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Gout
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Thanks to its diuretic and anti-inflammatory properties, meadowsweet is recommended for the prevention of gout.

Posologie

posologieOral: aerial parts

posologie250 - 1500 mg

formulationpowder, herbal tea/tea/infusion, dry extract


Cold
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Meadowsweet helps treat cold symptoms: fevers and headaches, thanks to its high salicylic acid content. The EMA and ESCOP recommend it as a traditional herbal medicine for supporting cold treatment.

Posologie

posologieOral: aerial parts

posologie250 - 1500 mg

duration7 days

formulationpowder, herbal tea/tea/infusion, dry extract


Cellulite
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Thanks to its remarkable diuretic properties, meadowsweet is an ally in the fight against cellulite; it promotes renal elimination of toxins and excess fluids by facilitating detoxification and drainage of subcutaneous tissues.

Posologie

posologieOral: aerial parts

posologie250 - 1500 mg

formulationpowder, herbal tea/tea/infusion, dry extract


Low Back Pain
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The EMA recognizes meadowsweet as a traditional herbal medicine for the relief of minor joint pain.

Posologie

posologieOral: aerial parts

posologie250 - 1500 mg

formulationpowder, herbal tea/tea/infusion, dry extract


Joint Pain
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The EMA states that meadowsweet is a traditional herbal medicine for the relief of minor joint pain, including low back pain.

Posologie

posologieOral: aerial parts

posologie250 - 1500 mg

duration4 weeks

formulationpowder, herbal tea/tea/infusion, dry extract


Gastric Ulcer
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Meadowsweet is traditionally used to treat gastrointestinal disorders associated with hyperacidity, such as gastritis, acidic dyspepsia, and gastroduodenal ulceration. It may promote the healing of chronic stomach ulcers caused by ethanol. There are currently no clinical studies confirming antiacid activity.

Posologie

posologieOral: aerial parts

posologie250 - 1500 mg

formulationpowder, herbal tea/tea/infusion, dry extract


Properties


Analgesic

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Salicylic aldehyde, a precursor for the production of acetylsalicylic acid (aspirin), has been isolated in large quantities from the flower buds of meadowsweet.

Usages associés

Cold, Low Back Pain, Joint Pain

Anti-inflammatory

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Salicins in meadowsweet, transformed into salicylic acid after absorption, reduce the synthesis of prostaglandins and thromboxanes by inactivating cyclooxygenase. Additionally, due to its high tannin content, meadowsweet has a strong in vitro inhibitory activity on elastase. To recall, elastases can play a pathological role in pulmonary emphysema, cystic fibrosis, infection, inflammation, and atherosclerosis.

Usages associés

Gout, Cold, Low Back Pain, Joint Pain

Platelet Anti-aggregants/Anticoagulant

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Meadowsweet flowers contain heparin linked to plant proteins. This complex has significant anticoagulant and fibrinolytic activity.


Antioxidant

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Meadowsweet extracts show high antioxidant activities, as demonstrated by the inhibition of the oxidation of methyl linoleate. The antioxidant activity of meadowsweet extracts has also been studied for use as a preservative in margarine.


Antibacterial

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Flavonoids and salicylic acid have antibacterial effects, especially against staphylococci and E. coli.


Diuretic

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It facilitates renal elimination and accelerates diuresis (urine excretion).

Usages associés

Gout, Cellulite

Astringent

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Meadowsweet is astringent and leads to a decrease in capillary permeability, local vasoconstriction, and an anti-diarrheal effect.


Immunomodulatory

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Extracts from roots, herbs, and flowers have been studied for their effects on the immune system in laboratory experiments (in vitro). These studies have revealed that these extracts can modulate the immune system's function, notably by inhibiting a significant part called the "complement classical pathway." To better understand, the complement system is part of the immune system and plays a crucial role in defending against infections. It is made up of a series of proteins present in the blood, which activate in cascade to help eliminate pathogens such as bacteria and viruses. The classical pathway is one of the ways this system can be activated, generally in response to the recognition of antibodies fixed to the surface of a pathogen. Furthermore, the effect of these extracts on the proliferation of T cells (a type of immune cell) has also been observed.


Gastroprotective

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The decoction has been effective in preventing stomach lesions induced by acetylsalicylic acid in rats. It promoted healing of chronic rat stomach ulcers induced by 70% ethanol injection into the lumen or glandular part of the stomach. Note that Meadowsweet contains salicosides, metabolized to saligenin in the intestine, which is, after absorption, transformed into salicylic acid (and not into acetylsalicylic acid, see the article on willow) and does not have the undesirable effects of aspirin a priori.

Usages associés

Gastric Ulcer


Safety dosage

Adult from 18 years: 250 mg - 1500 mg

- Crushed plant substance in the form of an herbal tea: single dose of 1.5-6 g in infusion, daily dose: 2-18 g. - Plant substance in powder: single dose of 250-500 mg, daily dose: 250-1500 mg. - Tincture (1:5): single dose of 2-4 ml, daily dose: 6-12 ml.


Interactions

Médicaments

Antibiotics: weak interaction

Certain antibiotics such as tetracycline or penicillin can interact with meadowsweet and increase the risk of bleeding.

Paracetamol: weak interaction

Paracetamol can interact with meadowsweet and increase the risk of bleeding.

Aspirin: weak interaction

Meadowsweet contains salicin, a plant-based salicylate. Theoretically, meadowsweet could have an additive effect with other medications containing salicylate like aspirin. Salicin does not appear to have the antiplatelet effects of aspirin.

Non-steroidal anti-inflammatories: weak interaction

It is necessary to adjust the dosage of non-steroidal anti-inflammatory drugs (NSAIDs) and anticoagulants when combined with meadowsweet.


Precautions

Breastfeeding woman: avoid

Meadowsweet may increase uterine tone and could stimulate uterine activity.

Allergies: avoid

In individuals allergic to salicylate derivatives (aspirin) or those who must avoid aspirin due to other medication or certain medical conditions.

Nephritis: avoid

Possible nephrotoxicity when meadowsweet is combined with paracetamol.

Asthma: avoid

Theoretically, meadowsweet could exacerbate asthma due to its bronchospastic effects. Use cautiously in people with asthma.


Contraindications

Pregnant woman: prohibited

Meadowsweet may increase uterine tone and could stimulate uterine activity.

Child up to 18 years: prohibited

Counterindicated in febrile children, due to the risk of Reye's syndrome associated with salicylates consumption.