Eggshell Membrane: Benefits, Dosage, Contraindications

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Eggshell membrane is a natural product containing collagen, glucosamine, GAGs (glucosamine, chondroitin sulfate, hyaluronic acid), and keratin, among others. It has been shown that eggshell membrane can accelerate fibroblast cell division and increase their metabolic activity by improving collagen production. Eggshell membrane proves to be a valuable ally for skin and joint health. Its ability to reduce cutaneous inflammatory processes is particularly interesting. The use of Ovoderm®, formulated from this membrane, has proven its effectiveness in significantly improving skin elasticity, even in individuals without prior skin alterations. Additionally, Ovomet®, another formulation from eggshell membrane, has exhibited promising benefits in the treatment of arthritis in elderly individuals, paving the way for new therapeutic perspectives.

Other name(s) 

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Family or group: 

Super Food, Amino Acids

Active ingredients:

Glucosamine

Collagen

Hyaluronic Acid

Chondroitin


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Skin Health
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Taking Ovoderm®, even for a short period and at a low dose, significantly improved the skin’s protective function, strengthening its barrier. Results from a clinical study highlighted a significant increase in skin elasticity, accompanied by a visible reduction in skin fatigue and an increase in firmness. These benefits appear to be due to several factors: an increase in collagen and hyaluronic acid levels, a reduction in matrix metalloproteinase activity, the inhibition of collagen-degrading enzymes (collagenase) and elastin (elastase), and a reduction in skin inflammation. Although the study observed a trend towards a decrease in skin pigmentation, this variation did not reach statistical significance.

Posologie

posologieOral Route

posologie300 mg

formulationOvoderm


Wrinkles
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Ovoderm®, an innovative product based on eggshell membrane, positions itself as a promising solution in the fight against visible signs of skin aging, notably wrinkles. Its rich composition in natural elements like collagen and hyaluronic acid makes it particularly effective in improving skin health and appearance. Clinical studies have revealed that even a short-term, low-dose intake of Ovoderm® can strengthen the skin barrier, essential for maintaining skin hydration and protection.

Posologie

posologieOral Route

posologie300 mg

formulationOvoderm


Arthritis
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A study examined the efficacy of daily administration of 300 mg of Ovomet® for arthritis treatment in elderly patients. Participants, suffering from diagnosed arthritis, took Ovomet® for 50 days. The study showed a significant reduction in joint pain and stiffness and an improvement in functional capacity right at the start of the treatment. By the end of the treatment, the majority of patients experienced a significant improvement in pain and functionality. These results suggest that Ovomet® could be an effective natural alternative for managing pain caused by osteoarthritis, thus improving the quality of life.

Posologie

posologieOral Route

posologie300 mg

formulationOvomet


Joint Pain
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The daily intake of 300 mg of Ovomet® for 50 days showed a positive effect on the linear stiffness of the Achilles tendon in elderly patients.

Posologie

posologieOral Route

posologie300 mg

formulationOvomet


Properties


Dermatological Effect

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A study showed a significant improvement in the skin's barrier function, elasticity, firmness, and fatigue following the consumption of a patented Ovoderm® extract. The study demonstrated that Ovoderm® can prevent and reduce the progressive loss of skin elasticity and firmness, characteristics of aging skin. These beneficial effects are likely linked to the increase in collagen and hyaluronic acid levels, the reduction of matrix metalloproteinase activity, and the inhibition of skin inflammation.

Usages associés

Skin Health, Wrinkles

Anti-inflammatory

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A study examined the impact of eggshell membrane hydrolysates on the activation of nuclear factor kappa B (NF-κB), a key element in the immune and inflammatory response. The results showed that these hydrolysates significantly activate NF-κB, suggesting a potential anti-inflammatory role. This mechanism could explain the beneficial effects observed in vivo, particularly in inflammatory diseases such as arthritis.

Usages associés

Arthritis, Joint Pain


Safety dosage

Adult: 300 mg

Studies indicate a dose of 300 mg per day of patented extract.