Arnica: benefits, dosage, contraindications

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Native to the mountainous regions of Europe, Arnica is a well-known perennial plant in phytotherapy. Its bright yellow flowers, with orange hues similar to daisies, grow in alpine meadows on acidic and well-drained soils. Arnica is used in phytotherapy and homeopathy for the treatment of minor traumas. However, its popularity has led to over-exploitation, threatening its availability in the wild. Nowadays, Arnica is subject to strict regulations to ensure its preservation. The entire flower heads, or Arnica flowers, are the main parts used in therapy. Harvested by hand during flowering, they can be used fresh or dried. Arnica is available in phytotherapy in the form of tinctures, creams, gels, and vegetable oils. The effectiveness of Arnica is based on its active components, notably sesquiterpene lactones such as helenalin, endowed with powerful anti-inflammatory properties. It also contains flavonoids and derivatives of caffeic acid, enhancing its antioxidant and healing effects. Traditionally used to treat bruises, sprains, and muscular pain thanks to its analgesic and anti-inflammatory properties, Arnica is also clinically recommended to reduce postoperative edema and pain, as well as to treat various skin inflammations.

Other name(s) 

The Gold of the Vosges

Scientific name(s)

Arnica montana

Family or group: 

Plants

Active ingredients:

Helenalin tiglate

Dihydrohelenalin


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Rheumatism
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As part of the treatment for rheumatic manifestations, Arnica has been the subject of several clinical studies aimed at evaluating its efficacy. An open clinical trial demonstrated that applying an arnica gel (A. Vogel Arnica Gel) twice daily for three weeks in people with osteoarthritis reduced total symptom scores, including pain, stiffness, and functional limitation, compared to initial measurements. Another larger randomized clinical study revealed that applying the same gel was as effective as ibuprofen for lowering pain intensity and improving hand function. The ESCOP indicates Arnica flowers, for external use, in the symptomatic treatment of rheumatism.

Posologie

posologieTopical application: flower

posologie50%

formulationgel, cream, oil


Sprain, Contusion, Bruises
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Arnica is widely used in minor traumatology, meaning in cases of non-open skin trauma, such as contusions, bruises, sprains, strains, or other injuries. According to the ESCOP (European Scientific Cooperative on Phytotherapy) and the EMA (European Medicines Agency), Arnica is recognized for these indications. Its efficacy is based on its traditional use. In clinical practice, Arnica shows promising potential in relieving postoperative symptoms and pain associated with injuries. Although some clinical studies suggest that topical products containing 10% Arnica, as well as oral homeopathic products, do not effectively reduce postoperative bruising, contradictory research highlights their benefits. For instance, one study showed that applying a 20% Arnica ointment twice daily for two weeks reduced laser-induced bruising compared to a white petrolatum-based ointment. Similarly, an Arnica-specific cream, applied four times daily, reduced periocular bruising in the first week after rhinoplasty compared to the absence of local treatment. Furthermore, the use of a specific oral homeopathic Arnica product demonstrated bruise reduction in women undergoing a facelift compared to a placebo, on days 1 and 7 postoperatively. A more recent clinical study examined the effect of topical application of Arnica or mucopolysaccharide polysulfate (MPSP) following lower wisdom tooth extraction. The results showed that the Arnica and MPSP groups experienced less pain than the control group until the fifth day. Arnica was more effective in reducing trismus, while MPSP was more effective in reducing swelling.

Posologie

posologieTopical application: flower

posologie10 - 20%

formulationgel, cream, oil


Muscular pain
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According to the ESCOP (European Scientific Cooperative on Phytotherapy) and the EMA (European Medicines Agency), Arnica is recognized for its use in treating localized muscular pain. The efficacy of Arnica in relieving muscular pain has been explored through several clinical studies, although the results remain contradictory. In one study, the topical application of a 7% arnica cream did not show significant reduction in muscle pain following calf-strengthening exercises. Another study revealed that although arnica applied immediately after intense exercise did not affect performance or indicators of muscle damage, it potentially reduced muscle tenderness three days later. Lastly, a study evaluating the effect of a mud poultice containing arnica and menthol indicated an acceleration of strength recovery and a significant reduction in muscle pain after intensive training sessions, although with no impact on muscle morphology.

Posologie

posologieTopical application: flower

posologie7 - 50%

formulationgel, cream, oil


Varicose veins
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A randomized double-blind study compared the topical application of a cream containing arnica flower extract to a placebo in patients with chronic venous insufficiency (primary leg varicose veins). After three weeks of treatment, combined with basic hydrotherapy, a significantly greater improvement was observed in the group who received the arnica-based treatment. However, another study, involving 100 patients divided into two groups of 50 each for treatment with either an arnica flower extract gel or a placebo, revealed comparable improvements in both groups, with no significant difference between the two groups.

Posologie

posologieTopically: flower

formulationgel, cream, oil


Gingivitis, Mouth ulcers
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According to ESCOP (European Scientific Cooperative on Phytotherapy) and EMA (European Medicines Agency), Arnica is recognized for its anti-inflammatory properties useful against gingivitis and mouth ulcers. The arnica-based product should not be swallowed. Local application or gargling.

Posologie

posologieOrally: flower

formulationgel, infusion, mother tincture


Insect bites
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According to ESCOP (European Scientific Cooperative on Phytotherapy) and EMA (European Medicines Agency), arnica is recognized for its anti-inflammatory properties useful against certain skin inflammations including insect bites.

Posologie

posologieTopically: flower

formulationgel, cream, oil


Properties


Anti-inflammatory

full-leaffull-leaffull-leafempty-leaf

The efficacy of Arnica against inflammation can be explained by the action of specific components such as helenalin. Studies have shown that helenalin possesses significant anti-inflammatory properties, illustrated by its ability to inhibit carrageenan-induced edema in rats in several animal model experiments. In addition to helenalin, Arnica contains sesquiterpene lactones, which intervene at the cellular level to inhibit the processes responsible for the initiation of inflammation. Thus, they block the activation of nuclear factor kappa B, a protein essential in triggering the inflammatory reaction, preventing the excessive production of molecules and enzymes that promote inflammation, such as pro-inflammatory cytokines, cyclooxygenase-2, and nitric oxide synthase.

Usages associés

Rheumatism, Sprain, Gingivitis, Varicose veins

Analgesic

full-leaffull-leaffull-leafempty-leaf

A study showed that sesquiterpene lactones, including helenalin present in Arnica, act as anti-inflammatory agents by inhibiting several biological pathways responsible for inflammation and pain, particularly the migration of polymorphonuclear neutrophils (white blood cells) to the injury site. These anti-inflammatory actions could contribute to their analgesic effects.

Usages associés

Rheumatism, Sprain, Muscular pain, Varicose veins, Insect bites


Safety dosage

Adult: 20% - 25% (mother tincture)

Arnica is used in various topical formulations, including gels, creams, ointments, oils, and dressings. For mouth rinses a 10% diluted tincture is used. Arnica is not recommended for oral use or for topical application on an open wound.


Precautions

Adult: use with caution

Orally, only homeopathic preparations are authorized. Ingesting arnica in any other form causes cardiotoxicity and severe side effects.


Contraindications

Pregnant women: forbidden

Arnica is contraindicated for both topical and oral use.

Breastfeeding women: forbidden

Arnica is contraindicated for both topical and oral use.

Allergies: forbidden

Arnica can cause immune reactions in people allergic to other plants in the Asteraceae family. Members of this family include chrysanthemums, marigolds, daisies, and many other plants.a