Aronia: benefits, dosage, contraindications

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Aronia is a genus of fast-growing deciduous shrubs in the Rosaceae family. This genus consists of only two species, Aronia melanocarpa and Aronia arbutifolia, both native to the same region in eastern North America and which can naturally hybridize, resulting in purple Aronia. Both species grow wild together in thickets or light woodland, on moist banks. Aronia was introduced to Eastern Europe, Asia, Scandinavia, and Russia in the early 20th century. Notably, it is extremely cold-resistant, withstanding Siberian temperatures of minus 30 °C. Its berries, low in calories, are edible. The small green berries turn red in Aronia arbutifolia and eventually black in Aronia melanocarpa. Aronia melanocarpa is distinguished by its clusters of black berries at maturity. The black berries have a slightly sour and astringent pulp. Traditionally, they were used as a remedy against colds by Native Americans. They are an excellent source of antioxidants beneficial for fighting cardiovascular diseases, obesity, or type 2 diabetes. The anthocyanins in Aronia berries can stop the growth of colon cancer cells. As such, Aronia's polyphenols may have a preventive effect on the growth and proliferation of different cancer types.

Other name(s) 

Chokeberry

Scientific name(s)

Aronia melanocarpa

Family or group: 

Plants

Active ingredients:

Flavonoids

Anthocyanins

Vitamin C

Vitamin B1

Vitamin B2

Oligo-Proanthocyanidins


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Metabolic syndrome
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Aronia berries are capable of reducing blood glucose and cholesterol levels, although clinical study results remain mixed. For metabolic syndrome, specific Aronia extracts at 300 mg per day for 2 months reduced systolic and diastolic blood pressure, as well as total and LDL cholesterol levels, without affecting blood glucose levels or body composition. Another extract at 30 ml per day for 4 weeks reduced body weight, LDL in women, and triglycerides in diabetic patients. Consuming juice containing Aronia for 6 months also lowered total cholesterol.

Posologie

posologieOral: fruit

posologie300 mL

duration3 - months

populationAdults

formulationjuice


Synergies


Cardiovascular diseases
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Aronia berries have shown positive effects on heart and vascular health. Aronia extracts have a beneficial effect in patients with metabolic syndrome. They significantly decrease triglyceride levels, serum LDL cholesterol, thereby regulating lipid profiles. In patients with hypercholesterolemia, a 2-month supplementation with Aronia significantly reduced cholesterol levels (-22%), lipid peroxidation (-40%), while improving membrane fluidity. Aronia extracts improve blood vessel function by reducing levels of a substance called ET-1, promoting cardiovascular health. They also have an anti-aggregant effect, preventing blood clot formation. Blood pressure is reduced by polyphenol extracts (anthocyanins and flavonoids) in hypertensive subjects. These extracts also enhance the endogenous antioxidant defenses (SOD, GSH-Px) of patients, potentially decreasing cardiovascular risks. While more clinical studies are needed, some studies clearly support their use for cardiovascular health.

Posologie

posologieOral: fruit

posologie300 mL

duration2 - months

populationAdults

formulationjuice

The polyphenol-rich extracts from black chokeberry and grape seeds impair changes in the platelet adhesion and aggregation induced by a model of hyperhomocysteinemia
Short-term supplementation with Aronia melanocarpa extract improves platelet aggregation, clotting, and fibrinolysis in patients with metabolic syndrome
Effects of aronia berry (poly)phenols on vascular function and gut microbiota: a double-blind randomized controlled trial in adult men
Aronia melanocarpa fruit extract exhibits anti-inflammatory activity in human aortic endothelial cells
Beneficial Effects of Polyphenol-Rich Chokeberry Juice Consumption on Blood Pressure Level and Lipid Status in Hypertensive Subjects
Evaluation of Antioxidant and Anti-Inflammatory Activity of Anthocyanin-Rich Water-Soluble Aronia Dry Extracts
Antithrombin effect of polyphenol-rich extracts from black chokeberry and grape seeds
In vivo influence of extract from Aronia melanocarpa on the erythrocyte membranes in patients with hypercholesterolemia
Extract from Aronia melanocarpa fruits potentiates the inhibition of platelet aggregation in the presence of endothelial cells
Combination therapy of statin with flavonoids rich extract from chokeberry fruits enhanced reduction in cardiovascular risk markers in patients after myocardial infarction (MI)
Anticoagulant effect of polyphenols-rich extracts from black chokeberry and grape seeds
Aronia melanocarpa extract reduces blood pressure, serum endothelin, lipid, and oxidative stress marker levels in patients with metabolic syndrome

Obesity
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Aronia demonstrates pancreatic lipase inhibitory activity in an oil emulsion model. It effectively inhibits triglyceride hydrolysis, leading to reduced lipid absorption. In a clinical study involving overweight or obese women with at least one cardiovascular disease risk factor, the daily consumption of 300 ml of a mixture of aronia, apple, blueberry, and cranberry juice for 6 weeks did not reduce body weight, BMI, or blood pressure. However, an improvement in total cholesterol and HDL levels compared to baseline measurements was observed.

Posologie

posologieOral route: fruit

posologie300 mL

formulationjuice


Synergies


Healthy Aging
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Aronia extracts, rich in polyphenols, can reduce the activity of certain genes involved in the progression of brain tumors, providing a promising avenue against glioblastoma. Furthermore, aronia juice stimulates the body's antioxidant enzymes, supporting its potential role as an anti-aging supplement. This dual action enhances interest in aronia for aging prevention and the fight against chronic diseases.

Posologie

posologieOral route: fruit

posologie200 mL

formulationjuice

Up-regulation of tumor suppressor carcinoembryonic antigen-related cell adhesion molecule 1 in human colon cancer Caco-2 cells following repetitive exposure to dietary levels of a polyphenol-rich chokeberry juice
Anticancer Effects of Extracts from Three Different Chokeberry Species
Induction of apoptosis and reduction of MMP gene expression in the U373 cell line by polyphenolics in Aronia melanocarpa and by curcumin
Preparative Purification of Polyphenols from Aronia melanocarpa (Chokeberry) with Cellular Antioxidant and Antiproliferative Activity
Antioxidant activities of chokeberry extracts and the cytotoxic action of their anthocyanin fraction on HeLa human cervical tumor cells
Effect of Supplementation with Black Chokeberry (Aronia melanocarpa) Extract on Inflammatory Status and Selected Markers of Iron Metabolism in Young Football Players: A Randomized Double-Blind Trial
Effects of anthocyanins on the prevention and treatment of cancer
Structure-function relationships of anthocyanins from various anthocyanin-rich extracts on the inhibition of colon cancer cell growth
In vitro antileukaemic activity of extracts from chokeberry (Aronia melanocarpa [Michx] Elliott) and mulberry (Morus alba L.) leaves against sensitive and multidrug resistant HL60 cells
Chemotherapy modulates the biological activity of breast cancer patients plasma: the protective properties of black chokeberry extract
Cytotoxicity of gemcitabine enhanced by polyphenolics from Aronia melanocarpa in pancreatic cancer cell line AsPC-1

Respiratory Infections
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By stimulating the immune response, aronia berries may have positive effects against upper respiratory tract symptoms. Indeed, due to their numerous antioxidant components, aronia berries could prevent flu and cold symptoms, as highlighted by their use in traditional medicine.

Posologie

posologieOral route: fruit

posologie100 mL

populationAdults

formulationjuice


Properties


Cardiovascular benefits

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Aronia seems beneficial for its preventive impact on the cardiovascular system. It has anti-inflammatory and anti-aggregating properties that limit clot formation. The polyphenols in Aronia could act by inhibiting the angiotensin-converting enzyme and through antioxidant effects, offering potential for the prevention and treatment of thromboembolic complications. Consuming Aronia improves blood circulation and the lipid profile of people at high cardiovascular risk, with cholesterol and triglyceride levels significantly reduced after 2 months of supplementation.

Usages associés

Cardiovascular diseases

Antioxidant

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Aronia anthocyanins have an antioxidant activity proven by laboratory, animal, and human research. Taking Aronia extract reduces pro-oxidant substances and modifies blood levels of antioxidant enzymes, like glutathione peroxidase and superoxide dismutase (SOD). In elite athletes, Aronia extract improves antioxidant enzyme levels, and in healthy adults, it increases the availability of reduced glutathione and the activity of glutathione peroxidase following exercise.

Usages associés

Cardiovascular diseases, Anti-aging

Hypoglycemic

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Diabetics could also benefit from Aronia berries, which are low in sugar. Possible mechanisms include the inhibition of enzymes involved in the digestion of carbohydrates and fats. Drinking 200 ml of Aronia juice daily for 3 months helped normalize blood sugar levels in people with type 2 diabetes.

Usages associés

Metabolic syndrome

Hypolipidemic

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Research indicates that Aronia can reduce plasma lipid levels in patients with hyperlipidemia or metabolic syndrome, although results vary among healthy subjects or those at cardiovascular risk. The beneficial effects on lipids may result from Aronia's antioxidant action rather than its influence on hepatic cholesterol metabolism. Moreover, Aronia may decrease intestinal cholesterol absorption.

Usages associés

Obesity, Cardiovascular diseases, Metabolic syndrome


Safety dosage

Adult: 200 mL (juice)

Aronia juice has most often been consumed at a dose of 200 to 500 ml per day for up to 12 weeks.


Interactions

Médicaments

Antiplatelet/Anticoagulant: moderate interaction

Aronia may have a blood thinning antithrombotic effect.


Precautions

Pregnant woman: use cautiously

To be consumed as part of a balanced diet and within dietary doses.

Breastfeeding woman: use cautiously

To be consumed as part of a balanced diet and within dietary doses.