Caraway: Benefits, Dosage, Contraindications

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Caraway is a biennial plant grown mainly for its seeds, valued for their aromatic flavor in cooking. Traditionally, these seeds are used for their carminative and aperitif properties, and also to stimulate lactation, akin to anise. The caraway fruit, used in therapeutics, must contain at least 30 ml/kg of essential oil to be effective. This yellow-green essential oil, present at about 3 to 7% in the fruit, is primarily composed of carvone (50-65%) and limonene (up to 45%), with less than 1.5% of carveol and dihydrocarveol. The fruit also contains 10 to 18% of vegetable oil, rich in petroselinic (30-43%), linoleic (34-37%), oleic (15-25%), and palmitic (4-5%) acids. Other constituents of caraway include about 20% proteins, 15% carbohydrates, phenolic acids mainly caffeic acid, and traces of flavonoids such as quercetin, kaempferol and their glycosides. Caraway seeds are recommended to relieve spasmodic gastrointestinal disorders such as flatulence and bloating, and are especially recommended for infant colic.

Other name(s) 

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Scientific name(s)

Carum carvi

Family or group: 

Plants

Active ingredients:

Carvone

Carveol

Limonene


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Flatulence, Digestive disorders
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Caraway is frequently used in combination with peppermint to alleviate dyspepsia symptoms. Clinical studies and a meta-analysis show that consuming a combination of 50 mg caraway oil and 90 mg peppermint oil, administered 1 to 3 times daily for 4 weeks, improves quality of life and reduces symptoms such as fullness sensation, pain, and mild gastrointestinal spasms. This combination would be as effective as cisapride in relieving dyspepsia and improving postprandial distress syndrome and epigastric pain syndrome. Another combination including caraway, peppermint, German chamomile, and other plants, taken 1 mL three times daily for 4 weeks, showed a significant reduction in symptoms such as acid reflux, epigastric pain, cramps, nausea, and vomiting. These results suggest caraway, used with other herbs, could be beneficial for treating dyspepsia.

Posologie

posologieOral: seed

posologie50 mg

duration4 - weeks

formulationinfusion, Carmenthin®, dry extract


Synergies


Digestive Spasms
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According to ESCOP, caraway is recommended for spasmodic gastrointestinal disorders such as flatulence and bloating.

Posologie

posologieOral: seed

posologie1.5 - 6 g

formulationinfusion, Carmenthin®, dry extract


Infant Colics
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According to ESCOP, caraway is recommended for gaseous colic in infants.

Posologie

posologieOral: seed

posologie1 - 4 g

formulationpowder, infusion


Lactation
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Traditionally used as a galactagogue to stimulate lactation, caraway shows no strong clinical evidence supporting this use. Studies note the presence of components like carvone in breast milk after consumption, but without demonstrating a significant effect on milk production. Some research suggests a possible increased acceptance of flavors by breastfed infants exposed to these dietary components.

Posologie

posologieOral: seed

posologie1.5 - 6 g

formulationpowder, infusion


Properties


Digestive effect

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Caraway essential oil locally stimulates the gastric mucosa, which activates the vagus nerve, leading to increased tone and rhythmic contractions of the stomach. This action promotes the expulsion of air from the stomach and increases gastric secretion, providing beneficial effects in managing digestive disorders like flatulence and bloating. Additionally, caraway may also positively influence bile flow, enhancing its role in facilitating digestion.

Usages associés

Flatulence, Infant colics

Antimicrobial

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Research on cell cultures shows that caraway extracts and oil have antibacterial activity against numerous organisms, including Bacillus cereus, Escherichia coli, and Staphylococcus aureus. Caraway essential oil is more active against gram-positive bacteria than gram-negative bacteria. Moreover, the oil showed significant antifungal and anti-Candida effects, maintaining its efficacy after gamma irradiation, indicating stability of the active components. These properties suggest potential use of caraway in antimicrobial applications, benefiting from a positive correlation between the limonene content of the oil and its antibacterial activity.


Antispasmodic

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A study explored the effects of Carum carvi (caraway) extract on guinea pig intestinal smooth muscle cells. The main mechanism of action observed is the reduction of muscle cell response to acetylcholine (Ach), a neurotransmitter that induces muscle contraction. Caraway extract showed a relaxing effect on smooth muscle cells, demonstrating dose-dependent inhibition of Ach-induced contraction. At the highest concentration tested (2.5 mg/mL), the extract significantly inhibited cell contractile response to Ach, which could partially explain caraway's effectiveness in relieving gastrointestinal symptoms like dyspepsia. Active components such as carvone and limonene may play a role in these antispasmodic effects by modulating enzyme activity or influencing the release of certain chemicals like prostaglandins, known for their effects on gastrointestinal motility and pain modulation.

Usages associés

Digestive spasms

Galactagogue

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Caraway is traditionally used as a galactagogue to stimulate breast milk production. Its components, particularly carvone, might promote lactogenic activity by increasing prolactin, a hormone essential for lactation. However, there is no strong clinical evidence supporting this use.

Usages associés

Lactation


Safety dosage

Adults from 10 years: 1.5 g - 6 g (seeds)

- Infusion: crushed caraway fruits (1.5 to 6 g), covered with 150 ml of boiling water and left to stand for 10-15 minutes. - Oil: 50 to 150 mg.

Children 4 to 10 years: 1 g - 4 g (seeds)

- Infusion: crushed caraway fruits (1 to 4 g), covered with 150 ml of boiling water and left to stand for 10-15 minutes.

Children 1 to 4 years: 1 g - 2 g (seeds)

- Infusion: crushed caraway fruits (1 to 2 g), covered with 150 ml of boiling water and left to stand for 10-15 minutes.

Infants up to 12 months: 1 g (seeds)

- Infusion: crushed caraway fruits (up to 1 g), covered with 150 ml of boiling water and left to stand for 10-15 minutes.


Precautions

Breastfeeding women: use with caution

Caraway is used to support lactation in the form of herbal tea. However, it is recommended to consult a healthcare professional before using caraway oil.


Contraindications

Pregnant women: prohibited

Caraway oil may stimulate menstruation.