Fermented Papaya: Benefits, Dosage, Contraindications
Other name(s)
Papaya
Scientific name(s)
Carica papaya
Family or group:
Plants
Indications
Rating methodology
EFSA approval.
Aging Well ✪✪✪✪✪
Fermented papaya is reputed for its anti-aging effects, largely due to its powerful antioxidant properties. A clinical study demonstrated that a daily intake of 9 grams of fermented papaya preparation for 4 weeks reduced oxidative damage to red blood cells, a key marker of oxidative stress. This effect theoretically contributes to preventing certain age-related degenerative diseases, such as neurodegenerative and cardiovascular diseases.
Posologie
Orally
3 - 9 g
Oxidative Stress in Patients with Alzheimer's Disease: Effect of Extracts of Fermented Papaya Powder
Skin Health ✪✪✪✪✪
Fermented papaya is a valuable ally for skin regeneration and overall skin health. An open study showed that a dressing made from partially ripe papaya promoted post-cesarean wound healing, notably by accelerating granulation tissue formation.
Posologie
Orally
3 - 9 g
Immune Strengthening ✪✪✪✪✪
The immunomodulatory effects of fermented papaya are well documented. It can support the body in fighting infections and promote an optimal immune response, essential for health maintenance, particularly in immunocompromised or aging individuals.
Posologie
Orally
3 - 9 g
Hair Loss ✪✪✪✪✪
Fermented papaya shows promising results against hair loss. A clinical study involving 154 alopecia sufferers revealed that a shampoo and lotion containing 2% fermented papaya significantly reduced hair loss while increasing hair density and diameter. These effects are attributed to a reduction of oxidative stress on the scalp, stimulation of cellular energy in hair follicles, and balancing of the scalp microbiome.
Posologie
Topical, Oral
3 - 9 g
Properties
Antioxidant
Fermented papaya is renowned for its powerful antioxidant effect, due to its ability to stimulate the body's endogenous defenses. Unlike traditional exogenous antioxidants, fermented papaya works by increasing endogenous production of glutathione and superoxide dismutase (SOD), two key enzymes that neutralize free radicals responsible for cellular aging and degenerative diseases. A clinical study showed that a daily intake of 9 g for 4 weeks reduced oxidative damage to red blood cells, suggesting protection against aging and certain chronic conditions.
Usages associés
Immunostimulant
Fermented papaya also acts as a natural immunostimulant. In vitro studies have demonstrated that it increases nitric oxide synthesis and tumor necrosis factor (TNF-alpha) secretion by macrophages. These actions strengthen the innate immune response.
Anti-inflammatory
Fermented papaya stands out for its notable anti-inflammatory action, largely due to its ability to modulate the activity of cytokines, molecules that orchestrate the inflammatory response. According to studies, fermented papaya acts by regulating inflammatory pathways and reducing the expression of pro-inflammatory cytokines such as IL-1beta and IL-6 while stimulating anti-inflammatory cytokines like IL-10. These effects have been particularly well-documented in the context of chronic inflammatory diseases, such as periodontal diseases. Moreover, these effects are reinforced by the biochemical richness of fermented papaya, notably its content in essential amino acids, minerals, and vitamins, which support tissue repair processes and reduce damage linked to chronic inflammatory stress.
Usages associés
Safety dosage
Adult: 6 g - 9 g
The dosages of fermented papaya vary depending on the formulations and indications. For oral intake, clinical studies used a dose of 9 grams per day for 4 weeks to demonstrate its antioxidant effects. For topical application, especially for skin care, products containing 2% fermented papaya have been successfully used, for instance, to reduce signs of skin aging or improve wound healing.
