Juniper: Benefits, Dosage, Contraindications

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Juniper is a shrub that grows wild in the mountainous regions of Europe. It bears fruit every two years, with berries that start green and turn blue-black when ripe. The famous alcoholic drink "gin" is made by distilling the berries of the juniper. In herbal medicine, the berries and essential oil of juniper are used. Juniper berries and leaves contain flavonoids, including apigenin, rutin, and luteolin. The essential oil of juniper berries is mainly composed of monoterpenes, such as alpha-pinene (51.4%), myrcene (8.3%), sabinene (5.8%), limonene (5.1%), and beta-pinene (5.0%). The seeds and fruits also contain glycolic acid, formic acid, malic acid, acetic acid, ascorbic acid, and camphor. Juniper extracts also contain potassium and phosphorus. Juniper is used for digestive problems, including intestinal flatulence, heartburn, bloating, and loss of appetite. It is also used for urinary disorders. The young shoots are considered remedies for the liver and gallbladder. The essential oil is anti-inflammatory and often recommended for joint and tendon issues.

Other name(s) 

Juniper berry, Common Juniper

Scientific name(s)

Juniperus communis

Family or group: 

Plants

Active ingredients:

Flavonoids

Potassium

Apigenin

Rutin


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Digestive disorders
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In cases of dyspepsia, juniper aids digestion and helps reduce flatulence and colics.

Posologie

posologieOrally: fruit, buds, leaf

formulationgemmotherapy, mother tincture, aqueous decoction


Urinary tract infections
✪✪✪✪

Juniper is highly recommended for cystitis. EMA indicates that the berries are used for minor urinary tract conditions.

Posologie

posologieOrally: fruit, buds, leaf

formulationgemmotherapy, mother tincture, aqueous decoction


Joint pain
✪✪✪✪

Juniper can help eliminate uric acid (uricosuric effect) and other toxins responsible for joint pain. The essential oil is anti-inflammatory, and topically, it could relieve sprains, tendinitis, and other musculoskeletal pains.

Posologie

posologieCutaneous, Oral: fruit, buds, leaf

formulationessential oil, gemmotherapy, mother tincture


Liver disorders
✪✪✪✪

Thanks to its hepato-protective properties, juniper's young shoots are indicated for liver problems: hepatitis, steatoses, and cirrhosis.

Posologie

posologieOrally: buds, leaf

formulationgemmotherapy, mother tincture


Properties


Diuretic

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The diuretic action of juniper has been attributed to 4-terpineol. However, some animal research suggests that the diuretic effect is partly due to the essential oil and partly to hydrophilic constituents. The significance of juniper's diuretic effects is unclear, as some animal studies show that juniper aqueous extract is no more effective than water in increasing urine volume, while other animal research only shows significant effects at higher concentrations.

Usages associés

Urinary tract infections

Antibacterial

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Juniper berry has demonstrated antibacterial effects in vitro. Juniper berries have shown activity against E. coli, S. aureus, and H. alvei. An extract of juniper leaves appears to have greater antibacterial activity than ethanol, methanol, and chloroform extracts.

Usages associés

Urinary tract infections

Analgesic

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Juniper seems to have some anti-nociceptive activity, potentially acting both peripherally and centrally. In animal research, a methanolic extract of juniper showed a dose-dependent effect on the writhing response. Additionally, intravenous administration of a lyophilized aqueous extract of juniper in mice produced a 178% analgesic response, as measured by thermal stimuli.

Usages associés

Joint pain

Anti-inflammatory

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Juniper fruit has been tested in the laboratory and shown to block the release of certain chemicals involved in inflammation, such as prostaglandins and a substance that activates blood platelets. When a juniper extract was orally given to rats, it significantly reduced paw edema caused by a substance called carrageenan. In fact, juniper extract decreased swelling by 60%, which is even more effective than indomethacin, an anti-inflammatory drug, which reduced swelling by 45% in this study.

Usages associés

Joint pain

Hepato-protective

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Juniper has demonstrated hepato-protective effects in animal research. Compared to rats receiving a placebo, rats receiving juniper and then exposed to CCl4 (a toxic product) had less pronounced increases in liver enzyme levels. Ethanol and aqueous extracts of juniper may be effective.

Usages associés

Liver disorders

Hypoglycemic

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In animals, juniper berries appear to lower blood sugar levels. They primarily work by increasing the peripheral uptake of glucose.


Safety dosage

Adult from 18 years: 2 g (infusion, mother tincture, liquid extract)

Herbal tea: 2 g of crushed or powdered plant substance in boiling water as an infusion, 2-3 times a day. Tincture: 1-2 ml 3 times a day. Gemmotherapy: between 15 and 30 drops depending on the preparation.


Interactions

Médicaments

Antidiabetics: moderate interaction

Juniper may reduce blood glucose levels. Taking juniper with antidiabetic medications might cause hypoglycemia. These antidiabetics include: glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase) and others.

Diuretics: minor interaction

Taking juniper with diuretics might cause excessive water loss in the body. Excessive water loss can lead to dizziness and an excessive drop in blood pressure. These diuretics include: chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Microzide) and others.


Precautions

Breastfeeding women: avoid

Safety during breastfeeding has not been established.

Children up to 18 years: avoid

Use in children and adolescents under 18 years of age has not been established due to a lack of adequate data. Avoid use.

Type 2 diabetes: use with caution

Juniper berries may reduce blood glucose levels. They could cause hypoglycemia (abnormally low) in diabetic individuals. Use with caution.

Hypotension: use with caution

Juniper berries may affect blood pressure and complicate its control.


Contraindications

Pregnant women: prohibited

The effects of juniper on the uterus could interfere with fertility or cause miscarriage. Juniper is not recommended for pregnant women or those seeking to conceive.