Lysine: Benefits, Dosage, Contraindications
Other name(s)
L-Lysine
Family or group:
Amino Acids
Indications
Rating methodology
EFSA approval.
Herpes ✪✪✪✪✪
Several clinical studies have demonstrated that oral administration of lysine monohydrochloride at doses between 1,000 and 1,248 mg per day or 1,000 mg three times a day reduces the recurrence of herpes labialis infections compared to a placebo. These results suggest that lysine could be an effective treatment for preventing herpes labialis outbreaks.
Posologie
Oral
1 - 3 g
Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis
Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride
Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis
Subjective response to lysine in the therapy of herpes simplex
Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis.
Clinical effectiveness of lysine in treating recurrent aphthous ulcers and herpes labialis
Sports Performance ✪✪✪✪✪
During endurance exercise, lysine oxidation increases. People who regularly engage in physical activity generally require more proteins to maintain optimal physical performance, though little data is available on this topic. Lysine supplements may be beneficial for athletes looking to enhance their sports performance and promote muscle recovery. Studies have shown that lysine supplementation can help reduce muscle breakdown and increase muscle protein synthesis after exercise, which can improve recovery and muscle growth. However, further research is necessary to confirm these effects and determine optimal lysine supplementation doses for athletes.
Posologie
Oral
4 - 6 g
The metabolic roles, pharmacology, and toxicology of lysine
Proteins and amino acids in post-exercise recovery
Metabolic effects of the association L-carnitine — L-lysine — methionine during maximal exercise
Emotional Balance ✪✪✪✪✪
Studies have suggested that lysine consumption can help reduce stress, improve mood, and manage anxiety. Preliminary clinical research has shown that consuming lysine-enriched wheat reduces stress in women and anxiety in men belonging to populations that generally consume cereal-based diets, compared to the control group. Though the underlying mechanisms are not yet fully understood, it is suggested that lysine may affect the production of neurotransmitters such as serotonin, which play a key role in mood and emotion regulation.
Posologie
Oral
4 - 6 g
Osteoporosis ✪✪✪✪✪
Research has demonstrated that lysine consumption can help increase bone density and reduce the risk of fractures in people with osteoporosis. Indeed, lysine promotes collagen synthesis, an essential protein for bone structure. Moreover, lysine plays an important role in calcium absorption, an essential mineral for bone health. Studies have shown that lysine supplementation can increase intestinal calcium absorption and reduce its urinary excretion, which can help prevent bone loss.
Posologie
Oral
400 - 800 mg
Properties
Metabolic
Lysine is an essential amino acid, one of the 20 building blocks of proteins. It plays a key role in the formation of collagen, bones, tendons, and blood vessels. Lysine also participates in the production of enzymes, antibodies, and certain hormones, which are necessary for growth and tissue repair, especially muscle tissue. Additionally, lysine contributes to optimal brain function by providing the necessary nutrients for the production of neurotransmitters such as serotonin, which regulates mood and emotions.
Usages associés
Musculoskeletal Effects
Lysine is an essential amino acid that plays a key role in protein synthesis and muscle protection. By promoting protein synthesis and reducing its breakdown, lysine helps preserve muscle mass and maintain strength and performance. Moreover, lysine stimulates the production of growth hormones such as insulin and IGF-1, which are necessary for stimulating muscle growth. It also increases the sensitivity of muscles to these hormones, enhancing their anabolic effects. In addition to its beneficial effects on muscles, lysine is necessary for collagen synthesis and may therefore be important for bone health. Studies have shown that calcium and L-lysine supplementation increases intestinal calcium absorption, while in vitro research has shown that lysine increases the cellular proliferation of osteoblasts.
Usages associés
Antiviral
Lysine is involved in the inhibition of viral replication by specifically blocking the enzymes necessary for viral protein synthesis. In vitro, lysine inhibits the growth of the herpes simplex virus.
Usages associés
Safety dosage
Adult from 18 years old: 1 g - 3 g
Lysine has been used at doses up to 6 grams per day for 8 weeks. It is most often used at doses up to 3 grams per day for up to 1 year.
Plantes ou autres actifs
Lysine: moderate interaction
Pharmacokinetic research shows that taking lysine with calcium can increase calcium absorption.
Precautions
Lactating women: avoid
Avoid the use of lysine due to insufficient information on its safety during breastfeeding.
Pregnant women: avoid
Avoid the use of lysine due to insufficient information on its safety during pregnancy.
