Oregano: Benefits, Dosage, Contraindications

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Oregano is a perennial herb from the Lamiaceae family, which also includes mint, thyme, marjoram, basil, sage, and lavender. Native to the warm temperate regions of Western Europe and the Mediterranean basin, oregano has spread widely and is now cultivated on most continents. The parts of oregano used include the leaves and aerial parts. In cooking, fresh or dried leaves are commonly used as an aromatic herb, while for therapeutic uses, its essential oil is widely utilized. Oregano essential oil is rich in volatile monoterpene phenols, notably carvacrol and thymol, which make up 70% to 85% of its content. These compounds are known for their powerful antibacterial and antifungal properties. Carvacrol, in particular, has been shown to be effective against various bacterial infections and can even enhance the efficacy of antibiotics through a synergistic effect. The efficacy of oregano is recognized for the symptomatic treatment of digestive disorders such as bloating, slow digestion, and flatulence, as well as for mild acute bronchial conditions. Oregano is also used for its beneficial effects on coughs related to ENT and bronchial ailments, feverish states, and colds.

Other name(s) 

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Scientific name(s)

Origanum vulgare

Family or group: 

Plants

Active ingredients:

Carvacrol

Thymol


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Wound
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A small clinical trial shows that applying an ointment containing a 3% concentration of oregano's water-soluble fraction twice daily for 10 to 14 days after minor dermatologic surgery could reduce infection rates and improve scar formation compared to a petrolatum-based ointment. Oregano promotes healing of minor skin inflammations and bruises, soothing damaged skin.

Posologie

posologieTopical

posologie3 %

formulationOintment


Digestive Disorders, Candidiasis
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Oregano is traditionally used to relieve mild gastrointestinal disorders, helping to improve digestion and reduce symptoms of discomfort, according to the EMA.

Posologie

posologieOral

posologie500 mg

formulationPowder, essential oil


ENT Infections, Bronchitis
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Oregano is recommended to alleviate cough associated with colds, helping to clear the airways, according to the EMA.

Posologie

posologieOral

posologie500 mg

formulationPowder, essential oil


Properties


Antibacterial

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Oregano essential oil and its component, carvacrol, possess significant antibacterial properties against a multitude of organisms, including antibiotic-resistant strains like methicillin-resistant Staphylococcus aureus. Phenols such as carvacrol and thymol, present in oregano, accumulate in the bacterial cell membrane, disrupting its structure and function, leading to leaks of potassium and phosphate ions, altering intracellular pH, and depleting ATP, essential for bacterial survival. These effects make oregano a widely used remedy against infections.

Usages associés

Digestive disorders, ENT infections, Wound

Antifungal

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Oregano essential oil and its component, carvacrol, demonstrate antifungal properties by inhibiting the growth of several pathogens such as Aspergillus species, Candida albicans, and Trichophyton mentagrophytes. They block the germination and mycelial growth of Candida albicans, significantly increasing survival rates in infected mice.


Antiviral

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Carvacrol has shown antiviral activity against the H1N1 influenza virus in the laboratory, though the necessary concentrations could be toxic to human cells.

Usages associés

ENT Infections

Hormonal Metabolism

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A study conducted on rats with polycystic ovary syndrome (PCOS) shows that oral administration of an oregano leaf extract at 250 or 500 mg/kg per day for 30 days indirectly increases fertility by improving markers associated with ovarian follicular development and hormonal anomalies in PCOS.


Safety dosage

Adult from 12 years: 500 mg - 1000 mg (powder)

- Infusion: 4 to 6 g for 250 mL of boiling water, infuse for 10 minutes, 3 times per day. - Encapsulated powder: 250 mg per capsule, 2 to 4 capsules per day. - TM: 5 to 10 drops, 3 times per day

Child from 7 up to 12 years:

1 to 2 drops essential oil.


Precautions

Breastfeeding women: avoid

Insufficient data.


Contraindications

Pregnant women: prohibited

Oregano is believed to have abortive and emmenagogue effects.