Cassia Fistula: Benefits, Dosage, Contraindications

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Cassia fistula, or Golden Shower, is a tree that grows in the tropical regions of Asia, reaching up to 6 meters. It is notably present in Pakistan and India. Its fruit is a brown pod containing several seeds and emits a strong odor considered to be unpleasant. The fruit has a high content of anthraquinones. Indeed, the fruits contain derivatives of 1,8-dihydroxy-3-anthraquinolone, rhein, fistuline, oxyanthraquinones, tannins, glycosides including sennosides A and B, volatile oils, as well as resinous and waxy derivatives. The leaves, bark, and fruits are used in traditional medicine for the treatment of skin infections and the elimination of toxins from the blood. The pulp of Cassia fistula is widely used as a laxative in traditional Chinese medicine (TCM) and Ayurveda to treat constipation.

Other name(s) 

Golden Shower, Indian Laburnum

Scientific name(s)

Cassia fistula

Family or group: 

Plants

Active ingredients:

Tannins

Anthraquinones


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Constipation
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A systematic review examined the effectiveness of Cassia fistula emulsion in the treatment of constipation. Two studies were included, both presenting a significant risk of bias. Analyses showed greater treatment success and increased frequency of defecation with Cassia fistula emulsion compared to control treatment. Moreover, Cassia fistula proved to be more effective than mineral oil and as effective as polyethylene glycol (PEG is an osmotic laxative used for the treatment of constipation). The most frequent side effects were diarrhea.

Posologie

posologieOral: bark, fruit

posologie4 - 8 g

populationAdults


Properties


Laxative

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Cassia fistula fruit is used for its laxative effect. Indeed, the pulp is included in preparations intended for the management of constipation. It is a mild stimulant for the intestines due to its high sennoside content. This laxative effect manifests in two ways: firstly, by altering colon motility to speed up intestinal transit, and secondly, by changing colonic absorption and secretion, leading to fluid accumulation and consequently diarrhea.

Usages associés

Constipation

Antipyretic

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The extract of C. fistula buds as well as the pod extract prepared in methanol exhibit significant antipyretic properties according to studies on rats. The doses used ranged from 200 to 400 mg/kg of body weight. The results of this study correspond to those obtained with paracetamol, a drug known for its antipyretic effects used against fever.


Antifungal

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The extracts of fruits, leaves, and flowers of Cassia fistula have shown important antifungal properties. Methanol and ethyl acetate extracts, in particular, have shown significant activity against various fungi, including Candida albicans and Alternaria solani. The efficacy is comparable to that of standard antifungal agents like clotrimazole.


Safety dosage

Adult from 12 years: 4 g - 8 g (pulp)

Some resources recommend between 4 and 8 g of fruit pulp. Prolonged use is not recommended.


Precautions

Pregnant woman: avoid

The use of Cassia fistula is not recommended for pregnant and breastfeeding women.

Child up to 12 years: avoid

The use of Cassia fistula is not recommended for children under 12 years.

Breastfeeding woman: avoid

The use of Cassia fistula is not recommended for pregnant and breastfeeding women.