Sulfur: Benefits, Dosage, Contraindications

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Sulfur is a chemical element essential for the proper functioning of the human body. As the third most abundant mineral in the human body after calcium and phosphorus, sulfur plays a crucial role in various physiological processes. Present at a quantity of 1.6g per kilogram of body weight, sulfur is essential for the integrity and elasticity of our tissues. It is notably a major component of amino acids such as methionine, cysteine, and taurine, which are fundamental for protein synthesis. These proteins play a key role in the formation and maintenance of body tissues, including bone cartilage and arterial walls. Sulfur can be found in garlic, onions, and broccoli. The risk of deficiency increases with aging. Historically, sulfur has been widely used in the treatment of various chronic pathologies, particularly musculoskeletal disorders like osteoarthritis and bronchial diseases. As a mucolytic agent, it helps reduce the viscosity of bronchial secretions, thus facilitating their elimination. This property is also exploited in certain thermal spas, where sulfur-rich waters are used to treat skin, respiratory, and rheumatic conditions. Sulfur’s role extends to the waste elimination processes at the hepatic level, supporting the breakdown of physiological metabolites, steroid hormones, and cholesterol. Additionally, it participates in the detoxification of toxic substances, including drugs and xenobiotics. Oligotherapy products containing sulfur are used in the management of allergic conditions, detoxification, and in the treatment of ENT disorders.

Other name(s) 

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Minerals and Trace Elements


Indications

Rating methodology

EFSA approval.

Several clinical trials (> 2) randomized controlled with double blind, including a significant number of patients (>100) with consistently positive outcomes for the indication.
Several clinical trials (> 2) randomized controlled with double blind, and including a significant number of patients (>100) with positive outcomes for the indication.
One or more randomized studies or multiple cohorts or epidemiological studies with positive outcomes for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or contradictory.
Lack of clinical studies to date that can demonstrate the indication.


Acne
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Sulfur is an ingredient used in medicine in over-the-counter topical products for treating acne, at concentrations from 3% to 10%. Although data on its efficacy is primarily anecdotal, creams and ointments containing 1% to 10% sulfur have been used for decades, often in combination with other agents like benzoyl peroxide or salicylic acid.

Posologie

posologieTopical application






Allergies
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A preliminary study indicates that a homeopathic nasal spray containing sulfur offers efficacy comparable to sodium cromoglicate nasal spray (an allergy medication) in relieving the symptoms of allergic rhinitis for 42 days.

Posologie

posologieNasal application


ENT Infections
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A preliminary study suggests that a homeopathic product containing sulfur relieves cold symptoms similarly to conventional remedies such as antihistamines, over a period of up to two weeks.

Posologie

posologieOral


Dermatoses
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Preliminary research shows that the topical application of 10% sulfur can effectively reduce the papules and pustules of rosacea, compared to oral tetracycline treatment.

Posologie

posologieTopical application


Chronic Obstructive Pulmonary Disease
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Preliminary research indicates that inhaling sulfur water shows no improvement in lung function in patients with obstructive pulmonary disease after 12 days of treatment.

Posologie

posologieInhalation


Detoxification
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Sulfur plays an important role in the detoxification of heavy metals through its compounds containing thiol groups, capable of binding these metals. This binding facilitates the excretion of metals, such as lead, mercury, and arsenic, thereby reducing their toxicity and accumulation in the body.

Posologie

posologieOral


Properties


Dermatological Effect

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Sulfur interacts directly with keratinocytes to transform into hydrogen sulfide through an unknown mechanism. This compound helps to break down keratin, leveraging its keratolytic action in the treatment of acne and seborrheic dermatitis.

Usages associés

Acne, Dermatoses

Antibacterial

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Sulfur shows activity against Propionibacterium acnes, a bacterium involved in acne. Its antimicrobial effects might result from its conversion into pentathionic acid (Vitamin B5) by normal skin flora or keratinocytes.

Usages associés

ENT Infections

Respiratory Effect

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Inhaling sulfur water is commonly used for respiratory disorders. Clinical evidence suggests that it might inhibit oxidative respiratory processes, offering potential therapeutic benefits in treating respiratory conditions.

Usages associés

Chronic Obstructive Pulmonary Disease, Allergies


Safety dosage

Adult:

Topical products containing sulfur at concentrations up to 10% have been used safely for periods of up to 8 weeks. There is insufficient reliable information available on the safety of oral sulfur use.


Precautions

Pregnant Women: use with caution

Topical products containing sulfur have been applied safely at concentrations up to 6%, for periods of up to 6 days. Avoid oral use of sulfur due to lack of reliable safety information.

Breastfeeding Women: use with caution

Topical products containing sulfur have been applied safely at concentrations up to 6%, for periods of up to 6 days. Avoid oral use of sulfur due to lack of reliable safety information.