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Should Type 2 Collagen be Preferred?

Doctorante en Pharmacie

Collagen is popular for its potential beneficial effects on youthful skin and joints. Should type 2 collagen be preferred, especially for joints?

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collagene type 2
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An editorial team specializing in nutrition. Authors of the book The Beneficial Foods (Mango Editions) and the podcast Food Revolutions.

Before becoming a supplement, collagen is an essential protein for humans. It is found in a large part of the body.

Bones, muscles, skin, synovial joints, blood vessels, and even tendons contain it. Its presence is not anecdotal as it is estimated to represent 30% of the body’s total proteins, making it the most abundant. 

Its action? To play the role of structure and aid in the resistance and elasticity of tissues. Collagen tightens the skin, facilitates bone movement, maintains good bone mineralization, and strengthens the durability of blood vessels. 

In the market, we find type 1 collagen, type 2 collagen, and sometimes blends. Are there cases where type 2 collagen should be preferred?

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Type 2 Collagen in Cartilage

To act throughout the body, our collagen slightly differs in composition and structure depending on its location. That’s why we don’t talk about just one collagen, but more than 20 types of collagens or variants, as indicated by this publication.

Thus, the skin contains a majority of so-called type 1 collagen, muscles and blood vessels are rich in type 3 collagen, while the joints are mainly supplied with type 2 collagen.

It is found within the cartilage, consisting of a viscous liquid that allows the sliding of different bones over one another without friction. It is precisely the collagen that gives it these properties. 

The Benefits of Type 2 Collagen for Joints

The presence of type 2 collagen is essential for cartilage health, as it helps it be more resistant and to better absorb shocks, notably in athletes. 

Collagen supplementation has already shown: 

  • a reduction in joint discomfort in athletes, in this 24-week study
  • an improvement in comfort and symptoms of osteoarthritis according to this 2019 meta-analysis

However, the scientific studies I could find do not necessarily use type 2 collagen. It is therefore difficult to know if the observed effects are attributable to a particular type of collagen or not. 

collagene articulation
Collagen allows cartilage to be more resistant. But should type 2 be preferred?

Should We Really Prefer Type 2 Collagen for Joints?

If type 2 collagen is present in the joints, it is not necessarily required to buy supplements that contain only this type of collagen

Indeed, in supplements, collagen is hydrolyzed: its structure no longer matters since the protein is broken down into small fragments.

It is only within the body that collagen amino acids can act and participate in the synthesis of the body’s native collagen. Although the structure of type 2 collagen is different from other types, it is no longer relevant here. 

As for using native type 2 collagen, its structure is far too large to pass through the intestinal barrier. It is therefore not useful directly through oral intake, as specified in the study

Finally, there is no scientific consensus today on the issue. Therefore, it’s impossible to determine the interest of type 1 collagen supplements versus type 2 when they are hydrolyzed.

Read also | 3 studies examine the effects of collagen on joints, what are the results?