Vitamin B8 Deficiency: Most Effective Supplements

Biotin, also known as vitamin B7, is an essential water-soluble vitamin that belongs to the B vitamin complex. It plays a key role as a cofactor for several biotin-dependent enzymes involved in vital metabolic processes, such as fatty acid synthesis, gluconeogenesis, and fatty acid catabolism. Discovered in 1942, biotin is often associated with hair, skin, and nail health, as well as the proper functioning of the nervous system. Biotin is primarily obtained through diet, although some intestinal bacteria can synthesize it.

Dietary Sources of Biotin

Biotin is found in small quantities in various foods, including organ meats, cow milk, and some fruits and vegetables. Among the biotin-rich food sources, liver, egg yolk, brown rice, lentils, and brewer's yeast are notable. These foods generally contain biotin bound to proteins, requiring enzymatic digestion to release free biotin, which is then absorbed by the intestine.

Symptoms and Consequences of Biotin Deficiency

While biotin deficiency is rare, it can have serious consequences if left untreated. Symptoms of biotin deficiency may include: • Muscle pain: Individuals with biotin deficiency may experience muscle aches and cramps. • Exhaustion and Fatigue: A lack of biotin can lead to a constant feeling of tiredness and exhaustion. • Loss of appetite: A decrease in appetite may also be observed in deficient individuals. • Desquamative Dermatitis: Biotin deficiency can cause red, scaly skin rashes, particularly around the eyes, nose, and mouth. • Nervousness and Depression: Neurological symptoms, such as nervousness, depression, and hallucinations, are common in biotin deficiency. • Skin and Hair Problems: A deficiency may lead to gray skin, hair loss, and hair discoloration. Populations at risk of biotin deficiency include individuals with hereditary metabolic disorders such as biotinidase deficiency, patients with intestinal malabsorption, pregnant women, as well as smokers and chronic alcoholics.

Supplementation and Prevention of Deficiencies

Biotin supplementation is often recommended to prevent and treat deficiencies, especially in at-risk populations. The common therapeutic dose is up to 10 mg per day to treat a biotin deficiency. Lower doses are used for prevention, generally around 0.3 mg per day.