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Ashwagandha, the Indian anti-stress root

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A mythical plant of Ayurvedic medicine, nicknamed the "Indian ginseng," ashwagandha is one of the most powerful natural stress relievers. But it doesn't stop at just one virtue! Let's take a closer look at a small root, the main ingredient of the famous Moon Milk, which might just change your life!

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Ashwagandha
✓ WHO ARE WE?
An editorial team specializing in nutrition. Authors of the book The Beneficial Foods (Mango Editions) and the podcast Food Revolutions.

VALIDATION SCIENTIFIQUE
Laure Fourchaud – 07.07.2021
Dr en physiologie de la nutrition

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Ashwagandha (Withania somnifera) is a plant from the Solanaceae family, like tomatoes and goji berries. Native to India, particularly from Madhya Pradesh, it also grows in the arid regions of Pakistan and Sri Lanka. It presents as a bush with long leaves and yellow flowers, produces small red berries, and can reach up to 1.5 meters in height.

But it is mainly its roots – and to a lesser extent its leaves, that have been traditionally used (about 3,000 years) for their various benefits for our body. The part of the plant that is the most rich in active ingredients, they are harvested when the rest begins to wither.

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First, and this is what explains its main properties, ashwagandha is an adaptogenic plant. This means it allows the body to adapt to physical and psychological stress it encounters.

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It sounds magical like that, but it’s a phenomenon closely studied by scientists since the 1950s and concerns other foods that interest us such as maca or ginseng.

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Its name comes from Sanskrit and means “horse smell”, referring to the strong odor of its roots, but also to the strength of equines. As for the small red berries it produces, they have earned it the nickname winter cherry in English.

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Studies have demonstrated the powerful anti-stress action of ashwagandha on our body. The active ingredients of this plant, especially its high concentration of withanolides, directly influence the production of cortisol, the so-called stress hormone. Research is also underway to demonstrate their anti-cancer action.

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  • Natural steroids: withanolides (including withaferin A)
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  • Antioxidants: tannins, flavonoids
  • Phenolic acids: gallic acid, vanillic acid, and syringic acid
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Ashwagandha is a plant that can help against stress and anxiety, as it helps to regulate and balance our cortisol production.

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It also helps to significantly reduce anxiety and insomnia. It is particularly recommended for sleep disorders, as it promotes a long restorative sleep.

Scientific studies:

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🏋🏻‍♀️ Strengthens the body and increases muscle mass

Consuming ashwagandha helps to strengthen the body and increase muscle mass. Its roots enhance physical condition and endurance.

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  • This study conducted by various hospitals and universities in India, demonstrates that ashwagandha supplementation in men aged 18 to 50 significantly promotes an increase in their muscle mass and strength.

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On the one hand, the reduction of stress and anxiety induced by its consumption results in improving attention and memory.

On the other hand, its antioxidant activity – thanks to the tannins and flavonoids it contains, protects nerve cells and our brain from the damage of free radicals.

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  • This study conducted by the National Institute of Mental Health and Neurosciences in Bangalore, India, demonstrated that the intake of concentrated ashwagandha extract had anxiolytic effects.

🍭 Balances blood sugar and reduces cholesterol

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  • This study from several Indian research centers would suggest that people who consumed the highest dosage of ashwagandha reduced their bad cholesterol levels by 17% and triglycerides by 11% on average.

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In powder form

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Its complementarity is also appreciated with spices such as ginger, cinnamon, and cloves. And strong essences such as vanilla.

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ashwagandha bio
Ashwagandha roots are ideal for decoction

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Sustainable Consumption: Opt for Organic and Fair-Trade Ashwagandha

✓ As usual, be sure to check the origin of ashwagandha and choose a biological product, free from pesticide residues and heavy metals, especially since you will likely be consuming its roots!

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⏳ Regarding the dosage of ashwagandha, it depends on how you want to consume the root. A 6-week course is recommended to fully enjoy its effects on stress and better sleep.

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Contraindications and Side Effects

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  • Those with autoimmune diseases
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As we have seen, ashwagandha is a pillar of Ayurvedic medicine. Today, it is no longer confined to traditional Indian medicine. It is part of many natural health products and blends, often paired with maca and cocoa, as a result of the growing interest in adaptogens.

The majority of ashwagandha available on the market comes from India, especially from the north of the country and Madhya Pradesh. Regions that traditionally cultivated wheat are now turning to ashwagandha cultivation, as local demand remains consistent, and international demand is on the rise. Additionally, the root is expected to be more profitable long-term than wheat.

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Detailed Nutritional Values

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Antioxidant compounds: catalase, superoxide dismutase, glutathione, flavonoids: kaempferol, catechin

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  • Phenolic acid: gallic acid, vanillic acid, benzoic acid, coumaric acid

Sources and scientific studies

Chandrasekhar K, Kapoor J, Anishetty S, 2012. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.

Wankhede S, Langade D, Joshi K, Sinha SR, Bhattacharyya S, 2015. The effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.

Ahmad MK, Mahdi AA, Shukla KK, Islam N, Rajender S, Madhukar D, Shankhwar SN, Ahmad S, 2010. Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males.

Choudhary D, Bhattacharyya S, Bose S, 2017. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.

Andrade C, Aswath A, Chaturvedi SK, Srinivasa M, Raguram R, 2000. A double-blind, placebo-controlled evaluation of the anxiolytic efficacy of an ethanolic extract of withania somnifera.

Biswajit Auddy, Jayaram Hazra, Achintya Mitra, Bruce Abedon, Shibnath Ghosal, 2008. A Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study.

Kakar SS, Ratajczak MZ, Powell KS, Moghadamfalahi M, Miller DM, Batra SK, Singh SK, 2014. Withaferin A alone and in combination with cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells.

Sangita Kumari and Alka Gupta. Nutritional composition of dehydrated ashwagandha, shatavari, and ginger root powder. International Journal of Home Science 2016; 2(3): 68-70.

Withania somnifera(L.) Dunal. PROTA (Plant Resources of Tropical Africa / Plant Resources of Tropical Africa). Wageningen, Netherlands: Gurib-Fakim A. and Schmelzer G. H. Retrieved 2012-08-07.

Withania somnifera(L.) Dunal. Germplasm Resources Information Network – (GRIN). Beltsville, Maryland: USDA, ARS, National Genetic Resources Program. National Germplasm Resources Laboratory. Retrieved 2011-10-29.

Alam N, et al. High catechin concentrations detected in Withania somnifera (ashwagandha) by high performance liquid chromatography analysis.BMC Complement Altern Med. (2011).

Singh B, Saxena AK, Chandan BK, Gupta DK, Bhutani KK, Anand KK. Adaptogenic activity of a novel, withanolide-free aqueous fraction from the roots of Withania somnifera Dun. Phytother Res. 2001 Jun;15(4):311-8. doi: 10.1002/ptr.858. PMID: 11406854.

Shenoy S, Chaskar U, Sandhu JS, Paadhi MM. Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists. J Ayurveda Integr Med. 2012 Oct;3(4):209-14. doi: 10.4103/0975-9476.104444. PMID: 23326093; PMCID: PMC3545242.

Widodo, N., Takagi, Y., Shrestha, B.G., et al., 2008. Selective killing of cancer cells by leaf extract of Ashwagandha: identification of a tumor-inhibitory factor and the first molecular insights to its effect. Clin. Cancer Res. 13 (7), 2298–2306.

2018, Royston KJ, Paul B, Nozell S, Rajbhandari R, Tollefsbol TO. Withaferin A and Sulforaphane Regulate Breast Cancer Cell Cycle Progression through Epigenetic Mechanisms. Experimental Cell Research.

Behrouz Hassannia, Emilie Logie, Peter Vandenabeele, Tom Vanden Berghe, Wim Vanden Berghe. Withaferin A: From Ayurvedic Folk Medicine to Preclinical Anti-Cancer Drug. Biochem Pharmacol.